Cardiology
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Brigatinib Tablets (Alunbrig)
Brigatinib is indicated for the treatment of patients with anaplastic lymphoma kinase-positive metastatic non-small cell lung cancer who have progressed on or are intolerant to crizotinib.
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Fludrocortisone for Orthostatic Hypotension Associated with Parkinson’s Disease
This double-center, double-blind, randomized, controlled trial compared the efficacy of pyridostigmine bromide vs. fludrocortisone and demonstrated that pyridostigmine bromide was not as effective as fludrocortisone.
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Risk Factors for Hospital Readmissions Ending in Death or Transition to Hospice
In this retrospective cohort study, multiple factors were identified during initial hospitalization, including sepsis and shock, that were associated with a hospital readmission within 30 days resulting in death or transition to hospice.
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Safe Treatment Recommendations for Benzodiazepine Dependence
There are clear, evidence-based treatment withdrawal regimens for benzodiazepine-dependent patients.
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Is Exposure to Arterial Hyperoxia During Critical Illness Dangerous?
Exposure to severe hyperoxia during critical illness is associated positively with increased ICU and hospital mortality and associated negatively with ventilator-free days.
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Health Benefits of Apple Cider Vinegar and Other Common Vinegars: A Review
A review of the literature to summarize the health benefits of apple ciider vinegar and other common vinegars.
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Coffee or Tea? Implications for Cardiovascular Health
A large, multi-ethnic study found that tea consumption was associated with slowed progression of coronary artery disease and lowered risk of cardiovascular events when compared to never drinkers; coffee intake appears to have no measurable effect.
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Homeopathy for Cold Symptoms in Young Children
A cough syrup containing homeopathic remedies improved cold symptoms more than placebo during the first day of treatment only.
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Predicting Electrical Cardioversion Failure
A study of the 30-day success rate of electrical cardioversion of acute atrial fibrillation revealed five clinical predictors of recurrence. These were combined into a risk score that could be useful to avoid unnecessary cardioversions in the acute setting.
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Tolvaptan Fails to Improve Dyspnea in Acute Heart Failure
In patients hospitalized for acute heart failure, adding tolvaptan to furosemide lead to increased weight and fluid loss, but did not improve dyspnea at 24 hours.