Cardiology
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Treating Erectile Dysfunction After Myocardial Infarction May Be Safe
In a Swedish nationwide cohort study of men < 80 years of age hospitalized for myocardial infarction, treatment for erectile dysfunction with phosphodiesterase-5 inhibitors resulted in lower mortality and heart failure hospitalization.
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Considering More Intensive Blood Pressure Control in the Elderly
In elderly, hypertensive patients, intensive blood pressure (BP) control (systolic BP < 140 mmHg) decreased major adverse cardiovascular events, including cardiovascular mortality and heart failure.
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Beetroot Juice and Aerobic Endurance and Blood Pressure
Researchers found that drinking beetroot juice daily improves submaximal aerobic endurance in patients with cardiac failure and preserved ejection fraction.
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Low Back Pain: Evidence for Nonpharmacologic Therapies
Developed for use in the new American College of Physicians guidelines, the authors reviewed evidence regarding non-pharmacologic interventions in treatment of low back pain.
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Insomnia Disorder: Evidence for Psychological and Behavioral Interventions
Cognitive behavioral therapy for insomnia (CBT-I) is an effective intervention for moderate to severe insomnia disorder and should be considered as an initial treatment.
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Tai Chi for Knee Osteoarthritis
Tai chi is as effective as a standard course of physical therapy in the treatment of pain of osteoarthritis of the knee.
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Study Challenges Orthodoxy of IV Hydration for Prevention of Contrast Nephropathy
SYNOPSIS: This trial randomized 660 patients with chronic kidney disease and a planned procedure requiring intravascular iodinated contrast to prophylactic hydration or to no hydration. No hydration was found to be non-inferior for prevention of contrast-induced nephropathy and saved significant costs.
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Clindamycin Improves Outcomes in Necrotizing Fasciitis due to Group A Streptococcus
SYNOPSIS: Using a murine model of necrotizing fasciitis, investigators determined that clindamycin inhibits key virulence factors of Group A Streptococcus, and should be given as soon as possible and at high doses to reach levels above MIC in affected tissues.
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Surviving Sepsis Campaign Guidelines Bundle: Studying How Improved Compliance Might Affect Outcomes
SYNOPSIS: Improved compliance with the Surviving Sepsis Campaign guidelines bundle was associated with a non-statistically significant decrease in the in-hospital mortality of severe sepsis patients.
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The ABCs of In-hospital Cardiac Arrest
SYNOPSIS: In this large, propensity-matched cohort study of patients who experienced an in-hospital cardiac arrest, patients who underwent endotracheal intubation had worse survival to hospital discharge than patients who were not intubated.