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Mean daily doses of up to 40 mg of prednisone equivalents and lengthy ICU stays were associated with impaired physical outcomes in patients who survived acute lung injury.
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In this retrospective study of extubation outcomes in five ICUs at a single medical center, patients extubated at night had no increase in adverse events and their mortality rates and lengths of ICU stay were lower.
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A DNA identification technique led this research group to postulate that many herbal products and herbal leaf samples were incorrectly identified and/or adulterated.
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Vitamin D3 supplementation in patients with persistent asthma and low serum vitamin D (25(OH)D) did not show improvement in the clinical efficacy of inhaled corticosteroids.
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A meta-analysis and systematic review found vitamin C supplementation improved endothelial function in patients with diabetes, atherosclerosis, and heart failure.
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Lipoic acid (LA) is a supplement that has much current interest for a variety of therapeutic reasons. Historically, its use as an antioxidant has been known for a long period of time.
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A study comparing experienced meditators and non-meditators found that the meditators had more favorable changes in some biochemical markers of stress-linked cell damage and inflammation. Those in both groups who responded more effectively to a stressful stimulus also showed somewhat better marker levels than those who responded less well.
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In this large prospective study of trauma patients, the most important factor associated with post-traumatic seizures was the presence of alcohol intoxication.
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A large, multicenter clinical trial that compared protocol-based care to usual care for patients presenting to emergency departments with early sepsis and septic shock found no differences in clinical outcomes. However, early recognition and therapy was beneficial and should be the standard of care.
