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  • Anticoagulant Strategy for Device Implantation

    In this paper, the authors perform a systematic review and meta-analysis of published reports comparing anticoagulation management strategies around the time of cardiac rhythm device implantation. Using standard techniques, the authors searched the medical literature and identified studies that assessed two or more anticoagulation strategies around the time of cardiac rhythm device implantation.
  • Radial vs Femoral Access in STEMI

    Primary percutaneous coronary intervention (PCI) saves lives in patients suffering from ST-elevation myocardial infarction (STEMI).
  • Pharmacology Watch: Does Finasteride Cause Permanent Sexual Side Effects?

    Side effects of finasteride; new ruling on pharmaceutical companies paying generic manufacturers; and FDA actions.
  • A Better Technique for Ablation of Persistent Atrial Fibrillation?

    This paper discusses the clinical utility of impulse and rotor mapping to guide atrial fibrillation (AF) ablation and is a follow-up to the acute observations discussed in Clinical Cardiology Alert several months ago.1 The authors hypothesized that AF is sustained by localized sources that may be targeted during AF ablation procedures.
  • Pharmacology Watch

    New treatment for prostate cancer; avastin and breast cancer; new CMS disclosure rule; and FDA actions.
  • Medical Therapy or Stenting for Aortoiliac PAD?

    Peripheral arterial disease (PAD) can cause symptomatic claudication and it can reduce quality of life.
  • Asymptomatic Severe Aortic Stenosis

    The management of asymptomatic patients with severe aortic stenosis (AS) is controversial. Patients meeting standard echocardiographic criteria for severe stenosis have a variety of pressure gradients and flow rates that can be divided into four categories based on normal flow vs low flow (NF vs LF) and low gradient vs high gradient (LG vs HG), where LF is defined as a stroke volume index (SVI) of < 35 mL/m2 and LG is a mean gradient < 40 mmHg.
  • Rivaroxaban after Acute Coronary Syndrome

    After acute coronary syndromes (ACS), patients remain at risk for recurrent cardiovascular events. Antiplatelet agents are the mainstay of secondary preventive strategies aimed at reducing the rate of recurrent events.
  • Stroke Risk in Atrial Fibrillation

    The Asymptomatic Atrial Fibrillation and Stroke Evaluation in Pacemaker Patients and the Atrial Fibrillation Reduction Atrial Pacing Trial (ASSERT) tested two hypotheses.
  • Value of the ECG in Asymptomatic AS

    Although electrocardiogram (ECG) left ventricular hypertrophy (LVH), especially with ST-T changes (strain pattern), is known to be of prognostic value in patients with aortic stenosis, its valve in patients who are being followed is unclear.