Browse Cardiology General Articles by Topic

The History Matters!

How would you interpret today’s 12-lead electrocardiogram and long lead V1 rhythm strip if the history was that of an older adult with known coronary disease? Would your interpretation change if, instead, the patient was a younger adult with a known history of severe congenital heart disease, having been operated on a number of times as a child?

Paltusotine (Palsonify) Tablets

The U.S. Food and Drug Administration has approved paltusotine, the second oral (after octreotide), but first once-daily formulation for the treatment of acromegaly in adults.

Psychiatric Medications and Long QT Syndrome: A Safe Combination?

A retrospective study of patients with electrocardiogram long QT interval syndrome and psychiatric disease suggests that with proper pharmacologic treatment and counseling, the patients can be treated safely with psychiatric drugs known to increase the QT interval.

Psychiatric Medications and Long QT Syndrome: A Safe Combination?

A retrospective study of patients with electrocardiogram long QT interval syndrome and psychiatric disease suggests that with proper pharmacologic treatment and counseling, the patients can be treated safely with psychiatric drugs known to increase the QT interval.

Preventing Ventricular Arrhythmias with Potassium

A Danish randomized trial of augmenting serum potassium by diet or medications compared to usual care in patients with an implantable cardioverter defibrillator (ICD) has shown that modest increases in potassium resulted in a reduction in the composite endpoint of appropriate ICD therapy or hospitalizations for arrhythmias or heart failure, or death.

Is Anticoagulation Necessary in Pulmonary Arterial Hypertension?

A large French national registry observational study of the use of anticoagulants in patients with pulmonary artery hypertension of diverse etiologies enrolled over 11 years, and a meta-analysis of this study and four other national registry studies, showed that there was no association between anticoagulant use and survival.

Efficacy of Adding Aspirin to OACs for CAD Patients

A randomized, placebo-controlled trial of adding aspirin to oral anticoagulant therapy in patients with chronic coronary artery disease at high risk of atherothrombotic complications and major bleeding was stopped early because aspirin increased the risk of all-cause mortality. In addition, aspirin was associated with an increase in atherothrombotic complications and major bleeding.

Mechanical Aspiration for RSIE: Finally, Some Data to Inform a Growing Practice

In this registry of patients undergoing mechanical aspiration for right-sided infective endocarditis, technical success rates were high, with a modest but significant rate of procedural complications. Further research with randomized trials will be needed to better define proper patient selection.

Wellens’ Syndrome or Not?

Today’s patient is a middle-aged man who presented to the emergency department (ED) with a history of chest pain with exertion during the past two weeks. His chest pain had been increasing and was at its most severe level the day he presented to the ED. The initial serum troponin level in the ED was more than 10,000 ng/L. Does the clinical scenario suggest Wellens’ syndrome?

Statins for Abdominal Aortic Aneurysms

An analysis of two large, abdominal aortic aneurysm (AAA) screening populations from Denmark has shown that high-dose statin therapy reduces the rate of AAA growth, the need for repair, and adverse outcomes, such as rupture and death.