Viral Infections
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Recombinant Herpes Zoster Vaccine in a Medicare Population
Receipt of adjuvanted recombinant herpes zoster vaccine was effective in individuals older than 64 years of age and maintained its efficacy in immunocompromised individuals. Added benefit accrued from receipt of the second vaccine dose, even if its administration was delayed.
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COVID-19 Rebound: To Retreat or to Re-Treat
Re-treatment of non-immunocompromised patients with mild-moderate COVID-19 rebound with nirmatrelvir/ritonavir provided no significant benefit.
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Measles Testing of Persons with HIV
A Dallas County human immunodeficiency virus clinic review from 2015-2025 found that only 11% of people with HIV had documented measles immunity, with younger patients, white and Hispanic patients, and patients with low CD4 counts more likely to be seronegative.
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COVID-19 Rebound: To Retreat or to Re-Treat
Re-treatment of non-immunocompromised patients with mild-moderate COVID-19 rebound with nirmatrelvir/ritonavir provided no significant benefit.
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The Seasonal Surge: Influenza in the ED
Influenza outbreaks occur each year, with their nature and extent largely determined by the virus’s glycoprotein structure and antigenic properties. These outbreaks typically occur during the winter months and can confer high morbidity to the general patient population. Increased mortality rates are seen in children younger than 5 years of age, older adults, and those with chronic comorbid medical conditions.
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Preventing SARS-CoV-2 Infection with an Allergy Nasal Spray
Use of the antihistamine azelastine nasal spray was effective in preventing SARS-CoV-2 infection in young, healthy, vaccinated outpatients.
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The Health and Economic Burden of Long COVID in the United States
Researchers using a computational simulation model found that the current health and economic burden of long COVID already exceeds the cost of several chronic diseases and will continue to grow as COVID-19 cases increase.
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Fever in the Child Returning from Global Travel
Every year, a significant number of families travel internationally with children, who then have a high rate of febrile illness after returning home. While most travel-acquired infections are self-limited and mild, some diseases may rapidly become fatal, and early recognition and aggressive management can maximize the child’s outcome. This review presents a focused clinical approach to caring for a child returning from international travel with a fever.
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Epstein-Barr Virus and Pediatric Sepsis
A recent study of 320 children with sepsis suggests that previous Epstein-Barr virus infection is causally associated with immune dysregulation and fatal outcomes.
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The Health and Economic Burden of Long COVID in the United States
Researchers using a computational simulation model found that the current health and economic burden of long COVID already exceeds the cost of several chronic diseases and will continue to grow as COVID-19 cases increase.