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In May 2011, an emergency-response team from the US Centers for Disease Control and Prevention (CDC) traveled to South Sudan, attempting to assist in the investigation of the recent geographic clustering of an illness, suspected to be the nodding syndrome.
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In this issue: Drug shortages; metformin and cancer prevention; migraine prevention guidelines; and FDA actions.
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Outpatients with a diagnosis of either dentoalveolar or periodontal abscess or a diagnosis of gingival inflammatory infiltrates were randomized to receive either moxifloxacin 400 mg daily or clindamycin 300 mg QID, both for 5 days, in a prospective, randomized, placebo-controlled, double-dummy clinical trial design.
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This report details the occurrence of an infected, cellulitic lower extremity wound infection in a 70-year-old British woman secondary to an unusual Vibrio species, V. alginolyticus.
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During November, 2011, I attended separate meetings dedicated to exploring the incidence of antimicrobial resistance in two areas of the developing world, India and Cambodia. The first, sponsored jointly by the American Society for Microbiology (ASM), the European Society for Clinical Microbiology and Infectious Diseases (ESCMID), and the Indian Association of Medical Microbiologists (IAMM), was named the "International Workshop on Antimicrobial Resistance" and was held at the Haffkine Institute in Mumbai, India. Organized by Prof. Lance Peterson (ASM representative), Prof. Abhay Chowdhary (Director of Haffkine Institute), Prof. V. Ravi (President of the IAMM), and Prof. Guiseppe Cornaglia (President of ESCMID), the workshop brought together around 250 participants, principally from India, to discuss various aspects of antimicrobial resistance over a 2.5 day program.
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Beginning in November 2010, players from several NBA teams were reported as suffering from the "stomach flu". An investigation was launched, querying 400 players and 378 staff members whether they had experienced nausea and/or vomiting sometime between November 10 and December 20. In total, 21 players and 3 staff members met the case definition for acute gastroenteritis from norovirus, based on the presence of symptoms with or without a positive RT-PCR stool test for norovirus. These 24 individuals represented 13 different teams from 11 different states.
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The Advisory Committee on Immunization Practices (ACIP) set forth new guidelines in October 2011 for the use of a quadrivalent meningococcal conjugate vaccine (MenACWY-D) in children, ages 9 to 23 months, that are at increased risk for meningococcal disease.
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Acute mountain sickness (AMS) is a syndrome that can affect travelers who are not acclimatized and gain altitude too quickly, usually occurring above 2,500 m. (8,200 ft.) elevation.
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In this report, the new CDC recommendations for the concomitant use of isoniazid (INH) and rifapentine (RPT) administered weekly for 12 weeks as directly observed therapy (DOT) are detailed.
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In this issue: New treatment for TB; safety of dabigatran; quality of antidepressants; systolic hypertension treatment; and FDA actions.
