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In this issue: Statins and diabetes risk; new treatment guideline for diabetes; new pertussis vaccine recommendation; antibiotics and rhinosinusitis; fluoroquinolones and cystitis; and FDA actions.
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Currently, intravenous artesunate for the treatment of severe falciparum malaria is dosed at 0, 12, 24, 48, and 72 hours with a total dose of 12 mg/kg (5-dose regimen).
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Timely recognition and treatment of myocardial infarction (MI) are crucial if we are to achieve optimal outcomes for our patients. Silent ischemia, or the absence of classical symptoms of ischemia, may delay the diagnosis.
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This report attempts to catalogue the ballooning number of cases of C difficile infection (CDI) in the United States using available resources, including data collected from the IDSA Emerging Infections Program (which has a catchment area of 111 acute-care hospitals and 310 nursing homes); the 2010 National Health and Safety Network data, which covers 711 acute care hospitals in 28 States; and data derived from 3 CDI prevention programs in 3 different states.
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Recent efforts to treat a patient in hospital with acute pneumocystis pneumonia (PCP) were hampered by a lack of available injectable trimethoprim-sulfamethoxazole.
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A new topical preparation for the treatment of head lice has been approved by the FDA. Ivermectin is a macrocyclic lactone antibiotic that has been used orally both on and off label for head lice since 2001.
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Chagas disease is caused by the protozoan parasite Trypanosoma cruzi, endemic only to the Americas. Most cases occur in tropical Central and South America, typically in impoverished communities that impinge upon the rural transmission cycle of this organism.
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In October 2011, GeoSentinel, the global surveillance program of the International Society of Travel Medicine, first reported on the initial findings in probable cases of sarcocystosis among travelers returning from Malaysia.
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CDC received 1691 reports of malaria diagnosed in the United States in 2010, a 14% increase from 2009, and the highest number of cases since 1980 (n=1864). Among these cases, 1131 were US residents, 368 foreign residents, and 192 had unknown status.
