Emergency departments in the United States are frequently confronted with trauma patients with varying degrees of injury.
As a group, I find most emergency physicians skeptical of many of the "advanced" technologies used to treat chronic diseases. I attribute this to our biased experience with these patients; those who do well are not likely to come to the ED very often.
In this well-designed, randomized, placebo-controlled clinical trial of antioxidant supplements for Alzheimer's disease, there was no benefit, and some agents were associated with worse outcome.
An alternate-day steroid protocol appears to be just as efficacious as every-day steroids over the long term in a group of patients with undifferentiated polymyositis, with less serious long-term side effects.