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Continuation of combination therapy with donepezil and memantine appears to have a long-term beneficial effect for patients with moderate-to-severe Alzheimer's disease.
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Krabbe disease can rarely present in adults as a combined central nervous system disorder with polyneuropathy.
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In comatose survivors of cardiac arrest, early malignant EEG findings during therapeutic hypothermia correlated with higher serum neuron-specific enolase levels and poor neurologic outcome.
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Early cessation of prehospital seizures via an intramuscular injection of midazolam was at least noninferior, if not superior, to traditional intravenous lorazepam.
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Basilar artery occlusion (BAO) is a grave form of ischemic stroke that carries a high morbidity and mortality. The Basilar Artery International Cooperation Study (BASICS) is a prospective, observational, international registry of consecutive patients with BAO that was radiologically confirmed.
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The incidence of epileptic seizures is much higher in elderly patients with Alzheimer's disease than those who are elderly but non-demented.
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Pertussis, commonly known as the "whooping cough," is an infection of the upper respiratory tract leading to a protracted cough illness. Emergency physicians should become familiar with the diagnosis and management of this disease, given the potential of pertussis to cause serious morbidity and mortality in young infants and protracted illness in adolescents and adults. Furthermore, diagnosing and treating pertussis in a timely manner has a large public health impact, given its extremely contagious nature.
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Emergency department administrators are well aware that crowding in the ED is associated with poorer patient outcomes, longer hospital stays, and decreased patient satisfaction.
