Primary Care/Hospitalist
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Predictors of Response to a Specific Psychological Treatment in Chronic Low-Back Pain
A theoretical model employed to predict response to either mindfulness meditation, cognitive therapy, or mindfulness-based therapy in patients with chronic low-back pain showed evidence that this type of model may be useful in determining which patients are most likely to benefit from a specified intervention.
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Effects of Probiotics on Cognition and Falls Risk in Patients With Cirrhosis
Patients with cirrhosis and mild cognitive impairment and falls were randomized to a probiotic formulation vs. placebo. Probiotic treatment improved cognitive outcomes and reduced the risk of falls.
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Mortality and Vitamin D Supplementation: A Meta-Analysis
In this systematic review and meta-analysis of randomized controlled trials, researchers determined that when compared with placebo or no treatment, vitamin D supplementation alone was not associated with an increase in overall all-cause mortality, though there were some nuances based on vitamin D form and type of mortality.
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Iron Absorption in Iron Deficiency Anemia With Alternate-Day Dosing
In a cohort of 19 women with iron deficiency anemia, alternate-day doses of iron led to 40-50% more iron absorption compared to consecutive-day doses. -
Stopping Cannabis Improves Cognitive Function in Patients With Multiple Sclerosis
The authors of a recent study evaluated the effect of discontinuing cannabis use in patients with multiple sclerosis. Stopping cannabis led to significant improvements in memory, processing speed, and executive function.
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Bright Light Therapy in Depression and Insomnia Associated With Parkinson’s
Bright light therapy (10,000 lux intensity for 30 minutes twice daily) and a low intensity control light showed similar efficacy in treatment of depression associated with Parkinson’s disease; the bright light therapy showed some advantages in improving subjective quality of sleep.
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A Review of Atrial Fibrillation and Current Therapeutic Strategies: Part 1
This two-part series presents a review of the current evidence on atrial fibrillation. The first part includes its definition, classification, risk factors, comorbidities, evaluation, and acute management of newly diagnosed patients. The second part will focus on long-term management, including risk factor modification, rate and rhythm control measures, stroke risk stratification, and anticoagulation management.
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Semaglutide Tablets (Rybelsus)
Semaglutide is indicated as adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus.
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After Ischemic Stroke Related to Atrial Fibrillation, Direct Oral Anticoagulants Are Superior to Vitamin K Antagonists
Researchers investigated the benefits and risks of early anticoagulation following acute ischemic stroke, and compared the effects of direct oral anticoagulants vs. vitamin K antagonists.
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Amyloid, Tau, Neurodegeneration Diagnostic Framework to Predict Memory Decline Before the Onset of Dementia
In a population-based longitudinal study of older individuals without dementia, the inclusion of imaging biomarkers for amyloid, tau, and neurodegeneration modestly improved the ability to predict memory decline compared to a model that only used clinical data and APOE genotype.