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Thalamic Stroke and Sleep Impairment: An Experiment of Nature

In a detailed clinical and electrophysiological study of sleep patterns in 12 patients with thalamic stroke, comparing them with 11 patients who had extrathalamic stroke, the investigators identified a marked decrease in slow wave sleep activity in the group with thalamic stroke. The clinical significance of this finding is uncertain but may have an effect on daytime cognitive performance.

Researchers Can Remove Recruitment Barriers in Alzheimer’s Trials

What can be consolidated, made simpler, or translated? What data can be collected outside your research setting? How can you communicate better with prospective and current research participants?

Pilocarpine Hydrochloride Ophthalmic Solution 1.25% (Vuity)

Pilocarpine ophthalmic solution (OS) can be prescribed to treat presbyopia.

Intensive Monitoring for Asymptomatic Atrial Fibrillation Did Not Prevent Strokes

Screening with an implantable loop recorder resulted in dramatically higher rates of atrial fibrillation detection and ensuing anticoagulation, but without a significant decrease in risk of stroke or systemic embolism by six years of follow-up.

Importance of Age in the Application of Coronary Artery Calcium Detection

Using coronary CT strategy as a diagnostic first line in patients with symptoms suggestive of coronary artery obstruction revealed relying on the coronary calcium score alone is inadequate for younger patients with a higher frequency of non-calcified obstructions.

Reduce the Risk of Autoimmune Disease with Vitamin D, n-3 Fatty Acid Supplements

A randomized, controlled trial that included older adults showed vitamin D3 2,000 units daily or n-3 fatty acids 1,000 mg daily over five years reduced the incidence of autoimmune diseases 25% to 30%.

Looking Back, COVID-19 Vaccination Woes Were Predictable

Efficacy, protection duration, side effects, and FDA approval factored into decisions about choosing a COVID-19 vaccine.

Fluvoxamine Reduces the Risk for Hospitalization from COVID-19

Researchers found fluvoxamine (100 mg twice a day for 10 days) lowered the risk for hospitalization among high-risk outpatients diagnosed with COVID-19.

Tailoring Dietary Recommendations to Protect Cognitive Health

Preventing inflammation as patients age is becoming key focus of lowering dementia risk.

‘STRAUMA’ Protocol Activates Care for Patients with Concurrent Symptoms of Stroke, Trauma

Researchers designed STRAUMA specifically for patients who exhibit symptoms of stroke and show visible signs of trauma. Typically, EMS activates the protocol, but other emergency providers can call for it after an appropriate patient has presented to the ED. An activation pages stroke and trauma teams to respond so they can evaluate the patient jointly.