Browse Neurology Articles by Topic

Stroke Patients Visit EDs Often After Discharge from Hospital

Repeat visits to the ED are quite common, even for patients who experienced mild or moderate strokes and are managing their conditions at home. This suggests home care models for these complex patients are important to evaluate and modify, if needed, to improve long-term care outcomes.

Post-Exercise Premature Ventricular Contraction, or Aberrancy?

The ECG in the figure is a post-exercise tracing. There are four wider and slightly early occurring beats in the long lead rhythm strips. Are these beats premature ventricular contractions or premature atrial contractions conducted with aberration?

Nirmatrelvir and Ritonavir Tablets (Paxlovid)

The FDA has issued an emergency use authorization for the first oral regimen for the treatment of COVID-19.

Incidence, Prevalence, and Long-Term Consequences of Small Fiber Neuropathy

Small fiber neuropathy (SFN) associated with diabetes and other causes is more likely to progress to large-fiber polyneuropathy, deteriorate faster, and cause worse disability vs. slow progression with idiopathic SFN.

Coronary CT Angiography in the General Population

Coronary artery CT angiography in asymptomatic, middle-aged subjects without known coronary artery disease showed coronary atherosclerosis is common but mostly mild and appears in women after a 10-year delay.

Fish Consumption, Omega-3 Fatty Acids, and Cardiovascular Disease

Is there enough scientific evidence to suggest associations between fish consumption and risk of cardiovascular disease (or of mortality) among people who consume fish vs. those who do not?

Drinking More Coffee May Protect Against Cognitive Decline

Among adults older than age 60 years, heavier coffee consumption was associated with slower cognitive decline in executive function and less beta-amyloid accumulation.

Neuropathological Variability of NMDAR-Encephalitis

The neuropathological features of N-methyl-D-aspartate receptor (NMDAR)-encephalitis are described in an autopsy cohort of four patients — two diagnosed in life with comorbid brain disorders, and two diagnosed at autopsy and never treated. The two untreated patients had inflammatory infiltrates composed of perivascular and parenchymal T cells and B cells/plasma cells in the basal ganglia, amygdala, and hippocampus. The two treated patients had variable pathologies that reflected their underlying neurological disorders (lymphoproliferative disease and multiple sclerosis). Overall, the topographic distribution of inflammation in patients with NMDAR-encephalitis reflects the clinical symptoms of movement disorders, abnormal behavior, and memory dysfunction with inflammation predominantly observed in the basal ganglia, amygdala, and hippocampus. Loss of NMDAR-immunoreactivity correlated with disease severity.

Intravenous Immunoglobulin for Stable CIDP: Stop or Taper?

First-line therapy for chronic inflammatory demyelinating polyneuropathy is intravenous immunoglobulin (IVIG), but the timing and method for withdrawal of this treatment are uncertain. In a retrospective review of stable patients on IVIG, investigators at the National Hospital in London observed that there was no significant difference in the likelihood of deterioration or response to retreatment if IVIG was stopped abruptly or tapered slowly.

Neuropathological Findings in the Brains of Patients Who Died from COVID-19

In an autopsy study of 41 patients who died from COVID-19 in a single medical center in New York City, most of the brain pathology was the result of hypoxic-ischemic injury, infarction, and hemorrhage, with microglial activation and neuronophagia caused by inflammation. Studies for the presence of viral proteins were negative, and very low levels of viral ribonucleic acid were detected.