Neurology
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Men More Likely to Produce High-Risk, Dangerous Carotid Artery Plaques
Investigators found significant differences in mean total plaque volume between men and women. Men were more likely to experience intraplaque hemorrhage and produce lipid-rich necrotic cores with coexistence of calcifications. Men also were more likely to exhibit thin or ruptured fibrous caps or ulcerations in their atherosclerotic plaques.
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Pregnant, Influenza-Infected, and Hospitalized
Almost one-third of women age 15-44 years hospitalized with influenza were pregnant and almost 5% required intensive care.
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Weight Loss and Other Interventions to Alleviate Obstructive Sleep Apnea
Obesity is a primary cause of obstructive sleep apnea (OSA), and improvements in weight and other lifestyle factors can yield benefits for OSA and related comorbidities.
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Extend Life Expectancy by Achieving Type 2 Diabetes Therapeutic Goals
Investigators analyzed gains in life expectancy by achieving treatment goals, finding significant gains from lower body mass index, glycated hemoglobin, systolic blood pressure, and low-density lipoprotein cholesterol.
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Updated Aspirin Guidance from the U.S. Preventive Services Task Force
The authors of new recommendations advise avoiding initiating aspirin for primary prevention of cardiovascular disease in adults age 60 years or older, individualizing decisions based on characteristics and preferences for patients.
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Multiple Sclerosis Disease Burden May Be Underestimated
Prescription drug prices, indirect productivity loss drive care costs significantly higher for these patients compared to others.
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Posterior Myocardial Infarction, or deWinter T Waves?
The ECG was taken from an older man who complained of chest pain over the past month. The pain severity was even worse on the day he underwent imaging. How would you interpret the ECG?
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Dexmedetomidine Sublingual Film (Igalmi)
Dexmedetomidine can be prescribed for the acute management of agitation associated with schizophrenia or bipolar I or II disorder.
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COVID-19 Vaccine and the Menstrual Cycle
In a retrospective cohort analysis of prospectively tracked menstrual cycle data from the smartphone application “Natural Cycles,” the COVID-19 vaccine was associated with a less than one day change in menstrual cycle length and no change in menses length.
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The Association Between Cancer Mortality and Physical Activity for Middle-Aged and Older Patients
In a prospective cohort study of older U.S. adults, replacing sedentary behavior with physical activity was associated with a lower cancer mortality risk.