Browse Neurology Articles by Topic

Surgical Management of Infective Endocarditis

Although guidelines outline specific indications for surgery in infective endocarditis (IE), applying these recommendations in the clinical area is challenging. In order to understand these challenges, the International Collaboration on Endocarditis (ICE) conducted a prospective study to evaluate the factors that influence the decision with regard to surgical intervention in IE.

Intravenous Fluids in Patients With Acute Heart Failure

Volume overload is a hallmark of acute heart failure (AHF). In hospitalized patients, intravenous loop diuretics are the most commonly used treatment for decongestion and symptom relief. Intravenous (IV) fluids are routinely administered to hospitalized patients, although their use in patients with AHF seems counterintuitive. No previous study has evaluated the frequency and effects of IV fluid administration among patients hospitalized for AHF.

Do Corticosteroids Play a Role in the Treatment of Community-acquired Pneumonia?

Despite antibiotic therapy and hospital-based care, severe community-acquired pneumonia still carries a high risk for morbidity and mortality.

Intracranial Clot Extraction Results in Better Outcomes than Intravenous Thrombolysis Alone

This article will discuss three studies that have been recently published in the New England Journal of Medicine — MR CLEAN, ESCAPE, and EXTEND — regarding intracranial clot extraction for acute ischemic stroke

Restless Legs Syndrome and Post-polio Syndrome

Restless legs syndrome is prevalent in patients with post-polio syndrome and is associated with decreased quality of life and fatigue.

Update in Treating Neuropathic Pain

In an exhaustive review of the literature with a meta-analysis, the following medications were found to be most efficacious in the treatment of neuropathic pain: gabapentin, pregabalin, serotonin-noradrenaline reuptake inhibitors including duloxetine or venlafaxine, and tricyclic antidepressants.

‘The Butterfly Effect’ Explains Weather Triggering of Migraine

For about 13% of patients with migraine, a change in weather may be a trigger for some headaches; however, there is no specific perturbation in meteorological measures that is likely to predict a headache.

Autologous Hematopoietic Stem Cell Transplant for Relapsing-Remitting MS

Interim analysis at 3 years post-treatment of a study of high-dose immunosuppression and autologous hematopoietic stem cell transplant for relapsing remitting-multiple sclerosis demonstrates sustained disease control but also shows potential risks associated with this treatment.

Is Pediatric-onset Multiple Sclerosis a Neurodegenerative Disorder?

ABSTRACT & COMMENTARY: Pediatric-onset multiple sclerosis compromises age-expected brain growth.

Clinical Briefs

Modifying the Home Environment to Prevent Falls