Neurology
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Effects of Lifestyle Modifications on the Coronary and Carotid Atherosclerotic Burden
A look at how lifestyle changes, including dietary modifications and regular exercise, impact therapy for atherosclerotic cardiovascular disease.
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Diet Sodas: Are They Really Diet?
Over the past several decades, concerns about increased sugar consumption has led some experts to recommend the use of non-nutritive sweeteners (NNSs).1
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Endovascular Intracranial Clot Extraction Benefits Are Confirmed in Two More Clinical Trials
On April 17, 2015, the New England Journal of Medicine published the results of two randomized clinical trials of endovascular stent-retriever clot extraction for ischemic stroke, simultaneous with their presentation at the European Stroke Conference. These two studies, added to those presented and published at the International Stroke Conference in February, bring the total number of studies to five that have shown dramatic benefits of this therapy in appropriately selected patients with acute ischemic stroke.
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Hypothermia after Acute Traumatic Brain Injury Revisited
Hypothermia therapy is effective after severe traumatic brain injury for patients ages 50 years and younger. However, mortality was increased in patients treated with hypothermia who had diffuse injury with swelling on CT.
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Is Early MRI Warranted for Back Pain in the Elderly?
In an analysis of a large dataset from several large integrated health care systems of patients older than 65 years of age with new-onset low back pain, early spine imaging did not alter management or outcomes, but added considerable cost to their care.
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Does Traumatic Brain Injury Cause Sleep Disruption?
In a well-designed animal model of traumatic brain injury, a sleep disorder was induced that resembles, in many ways, what is observed in spontaneous human narcolepsy.
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Relationship Between Brain MRI Biomarkers and Cognition
In a prospective, longitudinal, cohort study of an asymptomatic, multi-ethnic Dallas community, brain MRI biomarkers measuring volume were associated with cognitive functions, as measured by the Montreal Cognitive Assessment.
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Neurologic Disease and Criminal Behavior – A Medicolegal Conundrum
Patients with frontotemporal dementia, primary progressive aphasia, and Huntington’s disease exhibited antisocial and/or criminal behavior.
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Clinical Briefs
Clinical Briefs on topics such as: Chronobiology and Insulin Glargine, Dual Add-on Therapy for Type 2 Diabetes When Metformin is Not Enough, and Might Long-term Dual Antiplatelet Therapy Be Better? Not
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Are Atrial Premature Complexes Benign?
Atrial premature complexes (APCs) are commonly observed on routine ECGs and believed to be harbingers of atrial fibrillation, especially in patients with cardiovascular disease. However, little is known about the long-term prognosis of APCs in the general population. Thus, these investigators from Japan analyzed the database of a large community-based cohort from 1993 to 2008 to determine the risks of APCs seen on the subjects’ baseline ECGs.