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Inappropriate Outpatient Antibiotic Prescribing: The Need to Target Urgent Care Centers

Urgent care centers, which are part of a growth industry, are responsible for a large proportion of antibiotic prescriptions, including inappropriate prescriptions for acute respiratory diagnoses.

Latent Tuberculosis Treatment With 4 Months of Rifampin Compared to 9 Months of Isoniazid

In an open-label trial, adults with latent tuberculosis infection were randomized to either four months of treatment with rifampin or nine months of treatment with isoniazid. The four-month rifampin regimen was non-inferior to nine months of isoniazid for prevention of active tuberculosis.

Vitamin C for Postoperative Atrial Fibrillation Risk

Vitamin C supplementation decreases the risk of developing postoperative atrial fibrillation.

Use of Amyloid PET Imaging for Diagnosis of Dementia

The use of amyloid PET scanning to assist in accurate diagnosis of patients with symptoms of cognitive impairment as well as frank dementia results in a change of diagnosis in at least 25% of patients.

What Is the Key ECG Finding?

Tafenoquine Tablets (Krintafel)

Tafenoquine is indicated for the radical cure of P. vivax malaria in patients ≥ 16 years of age who have received appropriate antimalarial therapy for acute P. vivax infection.

Initial Management of Patients With Medication-overuse Headache

As part of a randomized treatment trial for medication-overuse headache, a simple protocol that provided early advice on stopping excessive medications was effective in one-third of patients, even before any prophylactic medications were started.

Clinicians Prescribe Antibiotics for Excessive Duration in Patients With a Diagnosis of Acute Sinusitis

Clinicians inappropriately prescribe antibiotics most often to patients with a diagnosis of acute sinusitis for durations much longer than recommended.

Canagliflozin Reduces Risk of Heart Failure Hospitalizations for Diabetic Patients

In type 2 diabetes mellitus patients with a higher risk of cardiovascular disease, canagliflozin lowered the risk of cardiovascular death or heart failure hospitalization. Patients with pre-existing heart failure may experience even greater benefit.

Substance Abuse and Myocardial Infarction

Among patients ≤ 50 years of age with first myocardial infarctions, use of cocaine or marijuana increased the likelihood of an ST-segment elevation myocardial infarction and the subsequent risk of all-cause and cardiovascular mortality.