Browse Internal Medicine Articles by Topic

sTMS for Migraine Prevention

This observational study adds evidence for daily use of single-pulse, transcranial stimulation (sTMS) for the prevention of migraines.

Is Electroacupuncture the Answer to Stress Urinary Incontinence?

Following six weeks of every other day treatment, women treated with electroacupuncture in the sacral region reported less urinary incontinence than women receiving sham acupuncture in the same region.

All That Is Round Is Not Fungus: A Differential Diagnosis of Annular Lesions

Annular skin lesions commonly plague many primary care patients, but not all that is round is fungus. This article highlights the differential diagnosis of conditions that can mimic tinea.

Dual Antiplatelet Therapy for Minor Ischemic Stroke or TIA

These investigators undertook this study to evaluate the effect of clopidogrel plus aspirin, vs. aspirin alone, in an international population of patients who had minor ischemic stroke or TIA — Platelet-Oriented Inhibition in New TIA and Minor Ischemic Stroke (POINT).

Tenecteplase vs. Alteplase for Ischemic Stroke

In a recent trial, treatment with tenecteplase before thrombectomy was associated with a higher incidence of reperfusion and better functional outcome than alteplase if administered to patients with ischemic stroke within 4.5 hours of symptom onset.

Prodromal Symptoms Predict the Onset of α-Synucleinopathies

In this review of the common prodromal symptoms of α-synucleinopathies, such as Parkinson’s disease, dementia with Lewy bodies, and multiple system atrophy, the authors provided a potential framework for a timeline of the development of these conditions, starting with these prodromal symptoms.

Chemotherapy-induced Neuropathy in Childhood Cancer Survivors

Long-term symptoms and disability from chemotherapy-induced peripheral neuropathy occur in more than half of childhood survivors of cancer, with vinca alkaloids and platinum agents implicated most often.

Cannabidiol: Does It Help in Drug-resistant Epileptic Encephalopathies?

In this double-blind, placebo-controlled trial, the authors investigated the efficacy of adjunctive cannabidiol in a population of severe developmental epileptic encephalopathies and found some efficacy.

Ufmylation and Brain Development: Effects of Gene Mutations

Genetic mutations that can modify post-translational proteins and their interactions may result in serious developmental disorders of the brain. Ufmylation is such a process, and mutations in the genes that regulate this process may have profound effects on the developing brain.

Predicting the Risk of Late-onset Alzheimer’s Disease and Dementia Based on Common Genetic Variants

Using a genetic risk score of 23 common genetic variants and apolipoprotein E genotype could help stratify individuals into those very likely to those very unlikely to develop late-onset Alzheimer’s disease and dementia.