Internal Medicine
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Using Ketamine in the Critically Ill: A Clinical Review
This is a guideline for ketamine use in the appropriate clinical setting from the practicing intensivist’s perspective.
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Management of Spontaneous Coronary Artery Dissection
In the largest study to date about patients with spontaneous coronary artery dissection who underwent follow-up angiography, 95% of those who underwent repeat cath more than 30 days later showed spontaneous angiographic healing.
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Impact of Atrial Fibrillation on Survival in Patients With Severe Mitral Regurgitation
A large observational study of patients with severe mitral valve regurgitation due to flail leaflets revealed that atrial fibrillation at entry was associated with excess mortality.
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Who Needs a TEE Prior to Atrial Fibrillation Cardioversion?
A study of patients with atrial fibrillation or flutter undergoing transesophageal echocardiography showed a left atrial appendage thrombus in 8% overall and 4% in those appropriately anticoagulated.
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Medication First? Ablation First? Either Way, Make Weight Loss a Priority
Weight loss management and aggressive risk factor modification associated with slowing or even reversal of atrial fibrillation progression.
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Withdrawal of Medical Therapy Associated With Relapse in Recovered Dilated Cardiomyopathy
In patients with dilated cardiomyopathy and recovered ejection fraction, discontinuation of heart failure medical therapies was associated with a 44% risk of relapse within six months.
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Infectious Disease Alert Updates
Imagine: Multidrug-Resistant GC; A New Borrelia Species in the ‘Old World’
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Baloxavir Marboxil (Xofluza)
Baloxavir marboxil is a novel, oral, antiviral agent approved by the Food and Drug Administration (FDA) on Oct. 24, 2018, for the treatment of acute uncomplicated influenza in patients 12 years of age and older.
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Staphylococcus aureus on the Playground and in the Gym — Is It Inescapable?
Staphylococcus aureus, including methicillin-resistant S. aureus, is a frequent surface environmental contaminant on both children’s playgrounds and in adult fitness centers.
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Adenovirus and CNS Disease in Children
Forty-eight immunocompetent children with adenovirus-associated central nervous system disease were described. Thirty-eight percent of patients died or experienced permanent neurologic sequelae.