In a systematic review and meta-analysis of prospective studies examining the association between mental stress-induced myocardial ischemia (MSIMI) and adverse outcome events in patients with stable CAD, all existing investigations point to an approximate doubling of cardiovascular risk in patients with MSIMI.
The first in a new class of orexin receptor antagonists has been approved by the FDA for the treatment of insomnia. Orexins are hypothalamic neuropeptides that appear to have a role in maintaining wakefulness.
The American College of Physicians recommends against performing screening pelvic examination in asymptomatic, nonpregnant, adult women.
Detecting HIV early creates opportunity for treatment and reduces transmission risk.