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A new case-control study finds that increased levels of dichlorodiphenyldichloroethylene (DDE), which is the metabolite of the pesticide dichlorodiphenyltrichloroethane (DDT), are associated with an increased risk for Alzheimer's disease.
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Trochlear headaches should be considered in patients with new onset, constant, unilateral eye pain, especially when the pain is aggravated by eye movement.
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Most patients who develop cryoglobulinemia associated with hepatitis C infection will develop symptoms and signs of a symmetric, distal sensory neuropathy.
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The Multicenter Automatic Defibrillator Implantation Trial with Cardiac Resynchronization Therapy (MADIT-CRT) showed that implantation of a cardiac-resynchronization therapy with a defibrillator (CRT-D) in patients with left bundle-branch block (LBBB), Class I or II congestive heart failure (CHF), and an ejection fraction < 30% was associated with a significant reduction in heart-failure events over 2.4 years.
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Most current guidelines recommend exercise electrocardiographic (ECG) testing for suspected coronary artery disease (CAD) in patients who can exercise and have a normal resting ECG.
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In patients with stable coronary artery disease and atrial fibrillation (AF) on oral anticoagulants, adding antiplatelet agents is common and recommended in guidelines, especially during the first year after an acute coronary event or revascularization.
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The mortality benefit to percutaneous coronary intervention (PCI) is unquestioned when it comes to ST-elevation myocardial infarction (STEMI).
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In patients with severe degenerative mitral regurgitation (MR), surgery is clearly recommended in the presence of any symptoms.
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In a prospective study of 35 patients with newly diagnosed idiopathic intracranial hypertension confirmed by diagnostic lumbar puncture and treated with standard medication regimens, 43% of patients had excellent headache outcome at 12 months, with the major improvement seen within the first month of diagnosis.
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Unlike other neuromuscular disorders, physical exercise does not appear to worsen weakness in patients with Charcot-Marie-Tooth disease.
