Browse Internal Medicine Articles by Topic

The Relationship Among Step Count, Step Intensity, and Mortality in Adults

The authors of this observational study of 4,840 adults show an association between higher number of steps taken daily and lower all-cause mortality, lower mortality from cardiovascular disease, and lower mortality from cancer, but no association between intensity of steps and mortality in any of those areas.

COVID-19 and Steroids: Is There a Consensus on the Controversy?

A retrospective, single-center cohort study among 201 adults admitted with COVID-19 pneumonia revealed that risk factors associated with the development of acute respiratory distress syndrome (ARDS) and progression from ARDS to death included older age, neutrophilia, organ dysfunction, and coagulation derangement. Treatment with methylprednisolone may be beneficial for these patients.

First-Pass Success Rate Between Rocuronium and Succinylcholine in Emergent Out-of-Hospital Endotracheal Intubation

This randomized, single-blind, noninferiority trial compared rocuronium and succinylcholine for rapid sequence intubation. Rocuronium was noninferior to succinylcholine with respect to the primary endpoint of first-pass intubation success.

Improving Sepsis Outcomes: Raising the Bar

In addition to compliance with the sepsis bundles, how can critical care providers revolutionize and individualize sepsis care for optimal results?

Sports Participation with Isolated Bicuspid Aortic Valve

If they follow recommendations for restriction from competitive sports, more than one-third of children and young adults with isolated bicuspid aortic valves could be disqualified mainly for mild aortic dilatation.

Cheyne-Stokes Respiration in Heart Failure

A comprehensive cardiorespiratory study of stable systolic heart failure patients showed Cheyne-Stokes breathing in the awake, upright position is related to hypercapnia and is independently associated with a higher risk of cardiac death.

Can Antibiotics Sterilize an Infected Heart Valve Before Surgery?

In a study of the relationship between the duration of antibiotic therapy and a positive surgically excised heart valve culture in patients with infective endocarditis, researchers observed positive valve culture incidence decreases exponentially on antibiotic therapy for 14 days then plateaus with no effect after 21 days of therapy.

The Prognosis of Severe Mitral Annular Calcification

This retrospective review of the natural history of severe calcific mitral valve stenosis demonstrates such patients die often partly because of a high comorbidity burden and partly as a result of the valve stenosis.

Renal Denervation Makes a Comeback

This retrospective review of the natural history of severe calcific mitral valve stenosis demonstrated such patients have a high mortality partly because of a high comorbidity burden and partly because of valve stenosis. Although often symptomatic, symptoms did not predict mortality.

Insulin Lispro-aabc Injection (Lyumjev)

Lyumjev is indicated to improve glycemic control in adults with diabetes mellitus.