Internal Medicine
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Two Possible Mechanisms of Disease in COVID-19
COVID-19 infection may be associated with an increased risk of blood clotting and related thrombotic events, but there are insufficient data to support indiscriminately discontinuing medications that play a critical role in the management of chronic cardiovascular disease.
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Endovascular Treatment for Acute Basilar Artery Occlusion Is Safe and Effective
Patients with acute basilar artery occlusion treated by endovascular therapy within 24 hours of occlusion time had better functional outcomes and reduced mortality compared to those treated with medical therapy alone.
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MRI and Clinical Correlation in Lumbar Arachnoiditis
Arachnoiditis, a feared complication of various spinal surgeries and procedures, shows a variety of nonspecific abnormalities on magnetic resonance imaging investigation, but there are no specific imaging features that predict prognosis.
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Deep Brain Stimulation of the Cortico-Striato-Thalamo-Cortical Network May Be an Option for Refractory OCD
Deep brain stimulation can be a treatment option for refractory obsessive-compulsive disorder, but the results are not significantly better than lesioning procedures. Small sample sizes, diverse targets of stimulation, and inconsistencies in rating scales are limiting factors in the studies of this modality.
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Preventing and Treating Medication Overuse Headache
Patients with migraine who have an insufficient response to acute treatment medications, including triptans, risk developing medication overuse headache (MOH). The most successful treatment for MOH is withdrawal of the offending acute pain medications combined with early use of a migraine preventative medication.
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Epilepsy 2020: At the Crossroads of Telemedicine and Smartphone Technology
In this study, the investigators show the diagnostic value of video smartphone technology with regard to a seizure diagnosis as well as the ability of smartphone video to help distinguish epileptic seizures from nonepileptic events.
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A Population-Based View into the Incidence and Etiology of Papilledema
In a population-based study in Olmstead County, MN, during the period 1990 to 2014, the incidence of papilledema was 2.5/100,000 persons per year, and most patients were diagnosed with idiopathic intracranial hypertension.
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Mystery Malaise: Discovering and Defining Burnout
Despite 40 years of research, definitions of key terms and measures regarding burnout are not yet standardized, hindering efforts to compare studies and to evaluate efficacy of treatment. Signs of burnout, such as emotional depletion and poor energy, overlap with mental health diagnosis (depression and anxiety, for example), leading some to wonder if burnout is a subtype of a mental health disorder.
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Examining Ginger for Ulcerative Colitis
For people with mild-to-moderate ulcerative colitis and who have symptoms and serum markers of inflammation and oxidation, some preliminary findings demonstrate both benefit and no difference when using 2 grams of ginger daily for 12 weeks vs. placebo.