Internal Medicine Alert
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Long-Term NSAID Use May Lower Dementia Risk
In a prospective population-based study of nonsteroidal anti-inflammatory drugs, long-term use was associated with a reduced risk for dementia compared with short- and intermediate-term use.
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Beware Social Media Posts Promoting Medical Tests, Potential for Overdiagnosis
An analysis of widely viewed social media posts about five medical tests — full body magnetic resonance imaging, multicancer early detection, anti-Müllerian hormone, gut microbiome, and testosterone tests — found that 87.1% of the posts promoted benefits, while just 14.7% acknowledged potential harms and only 6.1% raised concerns about overuse or overdiagnosis.
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The Cause of the ‘Burning?’
The electrocardiogram (ECG) in the figure is from a man with a new and severe “burning” chest discomfort. On seeing this ECG, the paramedic team requested activating the cath lab. Would you have done the same?
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Aztreonam and Avibactam for Injection (Emblaveo)
The U.S. Food and Drug Administration has approved a new combination antibiotic for the treatment of complicated intra-abdominal infections where there are limited or no alternative options.
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Death Due to the ‘No Name’ Virus in Santa Fe
On Feb. 26, 2025, it was announced that the bodies of actor Gene Hackman and his wife and caregiver Betsy Arakawa had been found in their Santa Fe, NM, home
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Bacterial Vaginosis: Treat the Man, Too
In a randomized trial, treatment of the regular male partner with oral and topical agents was strongly associated with a reduced risk of recurrence of bacterial vaginosis in the female partner.
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Clinical Consequences of Alzheimer’s and Lewy Body Co-Pathologies
This large study of patients with cognitive impairment-assessed cerebrospinal fluid biomarkers, positron emission tomography imaging, and cognitive tests showed that those with evidence of both Alzheimer’s and Lewy body pathologies had greater cognitive dysfunction and faster progression than those with either pathology alone.
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Cardiovascular Risk with mRNA COVID Vaccines
A large, nationwide population study in Sweden of the risk of adverse cardiovascular events after messenger ribonucleic acid (mRNA) COVID-19 vaccinations has shown that, except for rare cases of myopericarditis, severe cardiovascular events, such as myocardial infarction, heart failure, and stroke, are reduced, probably because of the prevention of COVID infection.
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Measles Vaccination in Adults in 2025
The Centers for Disease Control and Prevention has updated measles vaccination recommendations.
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Arrhythmia Recurrence After Catheter Ablation of Atrial Fibrillation
An integrated nationwide medical and pharmacy claims database analysis of patients with new atrial fibrillation undergoing catheter ablation as first-line therapy has shown that 17% of patients required repeat ablation for recurrent atrial fibrillation despite the frequent use of antiarrhythmic drugs.