Internal Medicine Alert
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Does Childhood Adversity Affect the Menopausal Transition?
The number and timing of adverse childhood experiences in relation to puberty affect the risk of incident major depressive disorder in menopausal transition.
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Simple Prediction Tool Facilitates Diagnosis of Heart Failure With Preserved Ejection Fraction
In patients with unexplained dyspnea, a score based on six noninvasive criteria can predict the likelihood of heart failure with preserved ejection fraction.
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An Uncommon Cause of ST Elevation?
Are the ST-T wave abnormalities seen in the tracing with this article the result of early repolarization? Or is this likely to represent acute pericarditis?
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Amlodipine and Celecoxib Tablets (Consensi)
Consensi is indicated for patients for whom the treatment with amlodipine for hypertension and celecoxib for osteoarthritis is appropriate.
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Fish Consumption and Disease Activity in Rheumatoid Arthritis
A cross-sectional analysis using baseline data from participants in the Evaluation of Subclinical Cardiovascular Disease and Predictors of Events in Rheumatoid Arthritis (ESCAPE-RA) cohort study demonstrated biweekly consumption of fish significantly decreased pain and progression of RA sufferers.
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After the WHI: How Is Your Sex Life?
Women who discontinued systemic postmenopausal hormonal therapy following participation in the Women’s Health Initiative studies experienced an increase in vaginal and sexual symptoms.
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As-needed Inhaled Corticosteroid/LABA May Be Effective for Mild Asthma Control
In two randomized, double-blind, multicenter trials, symptom-triggered, twice-daily dosing of budesonide-formoterol was as effective in preventing severe asthma attacks as scheduled twice-daily dosing of budesonide-terbutaline, but not as effective in relieving symptoms.
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Erenumab-aooe Injection (Aimovig)
Erenumab-aooe, with a novel mechanism of action, is the first drug approved specifically for the preventive treatment of migraine.
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Differences Between Type 1 and Type 2 Diabetic Neuropathy
Microstructural nerve damage in distal symmetric diabetic neuropathy differs between subjects with type 1 diabetes (T1D) and type 2 diabetes (T2D). The predominant nerve lesions in T1D correlated with hyperglycemia and nerve conduction impairment, while the predominant lesions in T2D correlated with dyslipidemia.
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Planes, Pathogens, and Passengers: Infection Risk During Commercial Air Travel
Although air travel has been linked to transmission of respiratory infections, the actual risk of becoming infected during air travel is low. The risk is greatest, though, when seated within about two seats/rows of a contagious individual. Walking around the cabin increases the risk.