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Calcitonin Gene-Related Peptide Targeting Therapies for Migraine

Two randomized clinical trials showed that calcitonin gene-related peptide targeting therapies are effective and safe for primary headache disorders.

Are the Changes New, Recent, or Old?

Imagine examining the ECG in the figure below without any accompanying clinical information. How would one interpret this tracing? What might one suspect is going on?

Imipenem, Cilastatin, and Relebactam Injection (Recarbrio)

The FDA has approved a new antibacterial drug combination for complicated urinary tract infections and complicated intra-abdominal infections.

Hot Beverages and Esophageal Cancer

In a cohort of more than 50,000 people, there was a higher risk of esophageal squamous cell carcinoma in those who consumed higher quantities of mostly black tea at hotter temperatures.

Reducing Mortality in Stable Ischemic Heart Disease Patients

A multivariate analysis of a large registry of patients with stable ischemic heart disease revealed that beta-blocker use was associated with lower mortality only when prescribed in the first year after acute myocardial infarction.

Atorvastatin: What Is Good for the Heart Is Good for the Kidneys

For patients at risk of or who already have been diagnosed with cardiovascular disease and are taking atorvastatin, an added benefit is improved kidney function in a dose-dependent manner.

Glucagon Nasal Powder (Baqsimi)

Glucagon nasal powder is indicated for the treatment of severe hypoglycemia in patients (≥ 4 years of age) with diabetes.

EEG Reactivity for Prediction of Neurological Outcomes After Cardiac Arrest

Researchers found that EEG-R testing, by itself, is not sufficiently reliable to predict neurological outcomes after cardiac arrest.

Medication Errors When Patients Transition Out of ICU

Three factors associated with decreased odds of an error occurring were daily patient care rounds in the ICU, discontinuing and rewriting medication orders during the transition of care from the ICU to a non-ICU setting, and 16-20 ICU beds in the transferring ICU.

Blood Pressure Control: Exercise vs. Meds

A random-effects network meta-analysis demonstrated comparable reductions in systolic blood pressure among normotensive and hypertensive participants using either antihypertensive medication or exercise interventions.