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Women who had low serum 25(OH) vitamin D concentrations were observed to have a higher hip fracture risk independent of other factors.
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Topical agents, both as monotherapy and in combination, have shown efficacy in management of acne. Benzoyl peroxide (BPO) is one of the most commonly used agents, but despite excellent efficacy, the side effects of skin dryness, burning, erythema, and peeling are sometimes limiting effects of treatment.
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The ECG shown was obtained from a 60-year-old man who was seen in the office. How would you interpret this tracing if you did not have more information? Is there cause for potential concern?
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Inhaled salmeterol and fluticasone, singly or in combination, reduce the rate of decline of the FEV1 in patients with moderate-to-severe COPD.
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CT colonographic screening of asymptomatic adults identified 90% of polyps or cancers measuring 10 mm or more.
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Homocysteine (HCYS) has all the trappings of a first-rate cardiovascular risk factor: as strong an association with CVD endpoints as cholesterol, ease of identification, and simplicity of modulation. Trouble is, trials to date have been unable to show that reductions of homocysteine provide meaningful benefits to patients.
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Intensive hemoglobin A1c lowering does not reduce the rate of cardiovascular death, and results in an increase in hypoglycemic events.
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Among almost 6000 patients with COPD who were using other classes of respiratory therapies, the addition of tiotropium, compared with placebo, was associated with improvements in lung function, quality of life, and exacerbations during a 4-year period, but did not result in benefits in the rate of decline in FEV1.
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The FDA has extended the approval for the Human Papillomavirus Quadrivalent Recombinant Vaccine to include the prevention of vaginal and vulvar cancer. The vaccine, originally approved in 2006, is already approved for the prevention of cervical cancer and genital warts.
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Opinions on the consequences of marijuana use are wide-ranging: Some experts express grave concern that it may induce COPD, increase risk of lung cancer, promote the emergence of schizophrenia, and lead to "heavy drug" use; others essentially dismiss these (potential) adversities as inadequately established to permit accusations that marijuana has any commonplace serious adverse effects.
