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SSRIs increase the risk of upper gastrointestinal bleeding, and this effect is potentiated by concomitant NSAID or aspirin use.
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The excess risk of Achilles tendon disorders attributable to fluoroquinolone use was estimated to be 3.2 cases per 1000 patient-years, with most of that increase accounted for by patients 60 years of age and older who concomitantly receive corticosteroids.
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Prostate Cancer Screening; Can We Trust Home BP Measurement?; Systolic and Diastolic Dysfunction
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FDA Issues Black Box Warning Based on WHI Study; ALLHAT: Thiazide for Hypertension Treatment; Candesartan Effective Against Migraines; Cough! No Cold Relief from Echinacea; COX-2 Inhibitors and GI Benefits Could Be Overrated; FDA Actions
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Thiazide diuretics should be the first-step antihypertensives because they are less expensive and more effective than calcium channel blockers or ace inhibitors.
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The FDA has approved teriparatide (rhPTH[1-34]) for the treatment of osteoporosis in men and women.
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Depressed seniors fared better when treated by a team of primary care practitioners and psychiatrists.
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There is a physiological basis to geriatric frailty characterized by inflammation and elevated markers of blood clotting.
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In this review of outcomes from cardiopulmonary resuscitation among non-ICU inpatients in 3 urban teaching hospitals, no patient who had an unwitnessed cardiac arrest survived to discharge. Forty-four percent of patients with witnessed respiratory arrest returned to their homes, as compared with 13% of patients with witnessed cardiac arrest (21% for pulseless ventricular tachycardia or fibrillation, and 7% for pulseless electrical activity or asystole).
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The Metabolic Syndrome and Total and Cardiovascular Disease Mortality in Middle-Aged Men; Effects of Amlodipine Fosinopril Combination on Microalbuminuria in Hypertensive Type 2 Diabetic Patients; Relation Between Alcohol Consumption and C-Reactive Protein Levels in the Adult United States Population