Internal Medicine Alert
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Clinical Briefs
In this section: effects of testosterone treatment in older men; liraglutide safety and efficacy in patients with non-alcoholic steatohepatitis; and long-acting anticholinergics and beta agonists for COPD.
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Daclizumab Injection (Zinbryta)
Another option for the treatment of the relapsing form of multiple sclerosis.
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The Current Outlook for Cardiac Tamponade
In the modern era, cardiac tamponade is most commonly caused by malignancies with poor prognosis. As compared to older literature, iatrogenic causes have increased, most resulting from complications of percutaneous coronary intervention.
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Nature Nurturing Health
A national prospective cohort study of nurses found that higher levels of green vegetation were associated with decreased mortality.
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The Relationship Between Inactivity and Mortality in Heart Failure Patients
Physical inactivity in heart failure patients was associated with an increased risk of all-cause death and cardiac death but not with an increased risk of heart failure hospitalization.
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Clinical Briefs
In this section: Might a pharmacologic agent that improves insulin resistance be effective in secondary prevention of CV events?; subclinical thyroid disease status associated with mortality in elders; and is there an infectious disease that causes pathological aggression?
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Buprenorphine Implant for Subdermal Administration (Probuphine)
The FDA has approved the first buprenorphine implant for the treatment of opioid dependence.
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Optimal Antiplatelet Therapy for Secondary Prevention of Ischemic Stroke
Patients presenting with acute ischemic stroke often take aspirin on a regular basis for prevention of cardiovascular disease. The optimal antiplatelet therapy for secondary prevention has been uncertain in this setting.
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Prognostic Value of Coronary Calcium on Standard Chest CT Scans
Coronary calcium scan on standard CT scans performed for other indications is of equivalent prognostic value to that seen on ECG-gated coronary studies and should be included in radiology test reports.
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Does Dysbiosis Cause Multiple Sclerosis?
Increasing evidence suggests that dysbiosis, a disorder in the gut microbiome, leads to autoimmune diseases, including multiple sclerosis.