Infectious Disease
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IDWeek 2021: Baricitinib for COVID-19 Patients Receiving Invasive Mechanical Ventilation or ECMO
Baricitinib significantly reduced mortality in patients with COVID-19 receiving mechanical ventilation or extracorporeal membrane oxygenation.
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Prophylactic Probiotics Do Not Reduce the Risk for Developing Ventilator-Associated Pneumonia
A multicenter, randomized, placebo-controlled clinical trial revealed the use of prophylactic probiotics did not reduce the risk for developing ventilator-associated pneumonia or improve other outcomes for intensive care unit patients, compared to placebo.
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COVID-19 Vaccination and Myocarditis
Receipt of a COVID-19 mRNA vaccine is associated with a small but real risk of development of myocarditis, predominantly in young males. The vast majority of cases are mild, self-limited, and require no intervention.
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Contemplating the Next Pandemic
We have heard much about the inevitable “next pandemic” as viruses move and mutate through animals until they become infectious in humans. An example of this was published recently, revealing how an avian flu virus caused fatal infections in swans, seals, and a fox, a “terrestrial mammal” not usually vulnerable to such a virus.
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The Return of Flu: Signs Point to Possible Severe Season
A possible severe influenza season is on the horizon, in part because COVID-19 shutdowns and precautions led to a historically low flu season in 2019-2020, said Rochelle Walensky, MD, director of the Centers for Disease Control and Prevention.
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Booster Option for HCWs Approved as CDC Overrules Advisory Panel
Centers for Disease Control and Prevention Director Rochelle Walensky, MD, MPH, is defending her decision to overrule her own vaccine advisory committee after they voted against giving COVID-19 booster shots to healthcare workers, teachers, and other essential workers at occupational risk of infections.
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Delta Variant Spreads Exponentially in United States with Millions Unvaccinated
The delta variant of COVID-19 has spread exponentially in the United States, with 96% of counties reporting high (90%) or substantial (6%) transmission as of Oct. 8, 2021.
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Difelikefalin Injection (Korsuva)
Difelikefalin can be prescribed to treat moderate-to-severe pruritus associated with chronic kidney disease in adults undergoing hemodialysis.
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SARS-CoV-2 Rapid Antigen Testing in a Nursing Home Outbreak
Rapid antigen testing was accurate in detecting SARS-CoV-2 antigen when compared to polymerase chain reaction.
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Localized Slow Wave Sleep in the Awake but Inattentive Brain
Electroencephalogram studies of humans during periods of “mind wandering” and “mind blanking” have shown regional changes that suggest parts of the brain may be asleep while other areas are activated.