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Abrocitinib Tablets/Upadacitinib Extended-Release Tablets (Cibinqo/Rinvoq)

Abrocitinib and upadacitinib can be prescribed to treat adults with refractory, moderate-to-severe atopic dermatitis that is not adequately controlled with other systemic drug products, including biologics, or when using those therapies is inadvisable.

Booster Doses Effective Against Omicron

While vaccination provides protection against infection with omicron variant of SARS-CoV-2, high level protection from a need for hospitalization requires a booster dose.

Patients’ Goals During Long-Term Acute Care Hospital Stays

After a long-term acute care hospital stay, most patients will achieve goals of ventilator liberation, eating, drinking, and speaking, but many will not achieve independence in walking, grooming, toileting, or returning home.

Coffee and Tea: Drink Choice and Effects on Stroke, Dementia, and Poststroke Dementia

Moderate amounts of coffee and/or tea consumption were associated with the lowest hazard ratio of stroke and dementia, while coffee alone or in combination with tea was associated with a lower risk of poststroke dementia.

The Joint Commission Issues Safety Tips for Reprocessing Critical Gear

The guidance includes specific reminders about single-use devices.

Infectious Disease Alert Updates

Delayed HIV Diagnosis with Injectable PrEP; Fatal Wave of COVID-Associated Mucormycosis

How Certain Is a Negative Echocardiogram for Excluding Infective Endocarditis?

Applying the proposed strict negative criteria for infective endocarditis (IE) on the first echocardiogram indicated this approach largely prevented unnecessary repeat tests unless clinically indicated for continued suspicion of IE.

Menstrual Toxic Shock Syndrome

The authors reviewed 102 patients with menstrual toxic shock syndrome requiring intensive care over 16 years in France. Despite the severity of illness, there were no deaths.

Clostridioides difficile and Reduced Vancomycin Susceptibility

Growth inhibition of Clostridioides difficile isolates from patients in Houston and Nairobi is requiring increasing concentrations of vancomycin, raising concerns about therapeutic efficacy.

Omicron: Get Your Booster Dose!

While vaccination provides protection against the omicron variant of SARS-CoV-2, high-level protection from a need for hospitalization requires receipt of a booster dose.