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In this study, 8,402 patients from seven case-control series were examined in this trial. The series included Kenyan children with bacteremia, patients with tuberculosis (TB) in Malawi, Hong Kong, and Gambia, and patients with severe malaria in Gambia, Kenya, and Vietnam. Standard methods for genotyping selected genes in PBMCs were employed.
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Early antibiotic administration was associated with reduced likelihood of death, mechanical ventilation, and readmission (but increased risk of Clostridium difficile infection) among patients hospitalized for acute exacerbations of COPD.
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An analysis of more than 1 million persons in Alberta, Canada, showed that laboratory reporting of estimated glomerular filtration rate (GFR) beginning in 2004 resulted in more referrals to nephrologists, but no apparent improvement in outcomes.
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Patients with dementia and their physicians face the difficult decision to cease driving with little solid evidence to guide them.
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In the absence of contraindications, metformin is the preferred initial treatment for most patients with type 2 diabetes (DM2). Unfortunately, monotherapy is unlikely to maintain adequate glycemic control, requiring additional treatment.
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Women who used proton pump inhibitors had a modestly increased risk of spine, forearm or wrist, and total fractures, but not hip fractures.
