Of all the motivations to become an infectious disease doctor, this is one of the more unusual paths taken: lose most of one leg and nearly all of your life to a series of recurrent near pan-resistant bacterial infections that you've finally fought into remission but still have a 30% chance of coming back and trying to kill you.
As many as 10% may be non-responders
Historically, men with high-risk prostate cancer were believed to have low survival rates after definitive treatment with either surgery or radiation. However, long-term results of dose-escalated radiotherapy of doses ≥ 75.6 Gy, along with long-term androgen deprivation therapy (ADT), demonstrate 5-year survival rate of 92%, 5-year biochemical control rate of 82%, and symptomatic local failure rate of 0%. Death from prostate cancer was only 5.5% at 10 years in men treated with high-dose radiation therapy and ADT.
In a study of men in the Veterans Affairs health care system with low serum testosterone levels, the use of testosterone therapy was associated with an increased risk of mortality, myocardial infarction, or ischemic stroke.