Infectious Disease Topics
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Clinician Alert: XDR Salmonella Typhi Acquired in the United States
Nine patients in the United States with no travel history had typhoid fever due to extensively drug-resistant Salmonella Typhi.
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Ventricular Assist Device Infections: More Questions Than Answers?
Almost two-fifths of patients with left ventricular assist devices develop associated infections. The optimal appropriate management remains to be determined.
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Oral Moxifloxacin vs. Intravenous Ertapenem Followed by Oral Levofloxacin and Metronidazole for Acute Appendicitis
A randomized controlled clinical trial found that a seven-day course of oral moxifloxacin was not noninferior to two days of intravenous ertapenem followed by five days of levofloxacin and metronidazole in adults with uncomplicated acute appendicitis.
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Unexpected Pediatric Benefits of the COVID-19 Pandemic
Despite the global tragedy of the COVID-19 pandemic, clinical experience suggests that there also have been some favorable indirect effects of pandemic-induced lockdowns on pediatric health. Specifically, there are lower rates of unscheduled primary care visits, emergency department visits, and hospitalizations for medical problems – without an increase in incompletely managed serious diseases.
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Getting to the Super Bowl: Lessons from the NFL on Controlling COVID-19
Aggressive implementation of mitigation procedures with continual evaluations and adjustments allowed the National Football League to complete their season with minimal COVID-19 transmission.
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Virus, Variants, Vaccines
The emergence of SARS-CoV-2 variants may compromise the efficacy of current vaccines.
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Obesity Connected to Up to Half of All U.S. Diabetes Cases
Recent analysis reveals strong connection between body weight and type 2 diabetes.
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Community Health Centers to Receive COVID-19 Vaccine Doses
These facilities serve millions who live at or below the federal poverty line.
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Cabotegravir Extended-Release and Rilpivirine Injectable Suspension (Cabenuva) and Cabotegravir Tablets (Vocabria)
Cabotegravir/rilpivirine (CAB/RPV) should be prescribed to treat HIV-1-infected adults. This combination should replace the current antiretroviral (ARV) regimen in those who are virologically suppressed (HIV-1 RNA < 50 copies/mL) on a stable regimen with no history of treatment failure and no known or suspected resistance to ether CAB or RPV.
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Subclinical Influenza Infection in Healthcare Workers
Despite all precautions, influenza vaccination, handwashing campaigns, and messaging to staff not to come to work with respiratory symptoms, healthcare workers are an important source of nosocomial influenza and respiratory infection. Now, it is happening with COVID-19.