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Childhood Diarrhea — Judicious Use of Diagnostic Tests

In the United States, rapid diagnostic testing for panels of potential gastrointestinal pathogens in children increases the yield of identifying rare pathogens, but, overall, does not change length of stay for hospitalized patients or reduce hospital charges.

Staphylococcal Prosthetic Valve Endocarditis: Drop the Rifampin? And the Gentamicin?

In a retrospective study, the investigators failed to find evidence of benefit of adjunctive rifampin therapy in patients with staphylococcal prosthetic valve endocarditis.

Bacteremic Urinary Tract Infection in the Elderly — Sometimes It’s a Guessing Game

In elderly patients with bacteremic urinary tract infection (UTI), symptoms of UTI were present in only one-third of patients, only four-fifths had fever, and just three-fifths had an early diagnosis of UTI.

Extensive Loss of Health at Six Months in Survivors of COVID-19

A cohort study from the U.S. Department of Veterans Affairs found many survivors of COVID-19 had significant loss of health six months after their acute illness, with greater risk associated with severity of the acute infection.

AstraZeneca Reports 79% Efficacy for U.S. COVID-19 Vaccine Candidate

But NIH raises questions the about data.

Coalition Calls for More Federal Investment in Antimicrobial Resistance Prevention

Groups ask Congress for additional money for research, innovation, surveillance, and stewardship.

The Growing List of Long-Haul COVID-19 Symptoms

Swedish researchers observe rapid heart rate, dizziness in patients months after viral infection.

Measles Outbreak Cost Public Millions of Dollars

The 2019 re-emergence of this vaccine-preventable disease cost a single U.S. county more than $3 million.

Early Convalescent Plasma to Treat COVID-19 in Elderly Patients with Mild Symptoms

Administering convalescent plasma obtained from survivors of COVID-19 within 72 hours of onset of mild symptoms in elderly patients with the virus was associated with a significant reduction in the risk of development of severe respiratory disease.

COVID-19 Patients Can Be Managed Safely with Noninvasive Respiratory Techniques

In adult patients hospitalized with COVID-19 for one month, using a noninvasive respiratory protocol that encouraged high-flow nasal cannula, noninvasive mechanical ventilation, and self-proning did not result in any significant increase in mortality.