Browse Infectious Disease General Articles by Topic

Dual Therapy Using Doxycycline and Azithromycin Is Superior to Monotherapy for Treating Severe Scrub Typhus

A multicenter, randomized, double-blind, controlled trial from India found dual therapy with intravenous doxycycline and azithromycin is more effective than either agent alone for treating severe scrub typhus.

Golden State: Disseminated Gonococcal Infection

The diagnosis of disseminated gonococcal infection often is delayed, but the infection can most often be readily treated with ceftriaxone. Patients often lack urogenital symptoms.

COVID Transmission During Air Travel

Despite careful air filtration in flying aircraft, there still is some risk of disease transmission during flights.

Infectious Disease Alert Updates

California Firefighters at Risk for Cocci; Hyperglycemia and Diabetes with INSTIs; Positive Sputum in Extra-Pulmonary Tuberculosis

Using Wastewater Surveillance to Monitor Mpox Outbreak

Researchers evaluated the use of wastewater surveillance to monitor the mpox outbreak in California.

Comparison of Postoperative Antibiotic Regimens for Complex Appendicitis: Is Two Days as Good as Five Days?

In a pragmatic, open-label, randomized trial conducted at 15 hospitals in the Netherlands, two days of postoperative intravenous antibiotics for complex appendicitis was found to be noninferior to five days in terms of infectious complications and mortality within 90 days.

Does COVID Vaccination Prevent Car Crashes?

In a large Canadian study, lack of COVID vaccination was associated with an increased incidence of being injured in a car crash.

Fungal Meningitis After Epidural Injections — Again

An outbreak in Mexico of meningitis due to Fusarium solani has affected at least 79 patients who had received epidural injections; at least 35 have died.

Nationwide Outbreak of Extensively Drug-Resistant Pseudomonas aeruginosa Infections from Contaminated Eye Drops

An outbreak of extensively drug-resistant Pseudomonas aeruginosa infection has been traced to use of contaminated artificial tears.

A Rapid Molecular Test Improves Time to Appropriate Therapy and Mortality in Patients with CRE Bacteremia

A multicenter observational study of patients with carbapenem-resistant Enterobacterales bacteremia found that time to receipt of active antibiotic therapy and mortality were improved in those whose blood cultures underwent rapid molecular testing for the Klebsiella pneumoniae carbapenemase gene. The mortality rate was 10% with ceftazidime-avibactam compared to 31% with polymyxin monotherapy.