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A group of staphylococcal investigators from Lyon, France, and Houston, Texas, have been working for years to show the importance of toxins in the pathogenesis of S. aureus infections. The group of Jerome Etienne and Francois Vandenesch in Lyon have already shown the propensity of strains containing the PVL toxin to produce fatal necrotizing pneumonia in children.
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Quinolone-Resistant Neisseria Gonorrhea (QRNG) continues to spread with alarming frequency across the United States.
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IBS-Drug Treatment Pulled, CV Side Effects; Drug Combo Better for Migraine Treatment; Pergolide Off the Market, Heart Disease Risk; Hormone Treatment, Does Timing Matter?; FDA Actions
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This paper reports the results of an important multinational trial which evaluated the use of two different regimens of posaconazole in the treatment of OPC or EC which had been refractory to either fluconazole or itraconazole.
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The Advisory Committee on Immunization Practices (ACIP) has finally published its recommendations for the use of Gardasil, the quadrivalent human papillomavirus vaccine that has recently become available.
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Rotashield, a vaccine protective against rotavirus infection was withdrawn from the U.S. market because of an apparent excess risk of intussusception. The recent introduction of a new vaccine, RotaTeq, has inevitably led to concerns about an increased incidence of this complication in children receiving this vaccine, as well.
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This important study compared an outpatient cohort of 471 HIV-infected outpatients living in the Midwest to data files from the NHANES cohort of HIV-negative subjects matched by age, sex, race, and tobacco use.
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It has become in vogue to plan for influenza pandemics. What is not clear is what would be excess mortality in such a pandemic.
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From community-based active surveillance data in Antelope Valley, California, (northeast of Los Angeles) from 1995-2004, 9.5% (1,080 subjects) of all 11,356 subjects with varicella had onset of rash > 42 days after varicella vaccination, which defines breakthrough varicella. The diagnosis was confirmed by physician evaluation or laboratory test in 770 subjects (71.3%).