Browse Infectious Disease Alert Articles by Topic

Getting to the NBA Finals by COVID-19 Vaccine Boosting

Vaccine booster doses were highly effective in preventing infection, whether symptomatic or asymptomatic, with the omicron variant of SARS-CoV-2 in National Basketball Association players and staff.

Cirrhosis and Infections

Infections in patients with cirrhosis are frequent and potentially lethal, with pneumonia associated with the highest risk for mortality.

Influenza Vaccination Reduces the Risk of Major Cardiovascular Events

A meta-analysis of six randomized, controlled trials revealed receipt of influenza vaccination reduced the risk of major cardiovascular events compared to the unvaccinated, with 56 patients needing vaccination to prevent one event. Higher-risk patients had 45% reduced risk.

Travelers Need Pre-Trip Hepatitis A Vaccination

Hepatitis A continues to be a problem for international travelers in much of the world. More widespread use of hepatitis A vaccine could be warranted.

Monkeypox in the United States

The first 17 patients in the United States affected by the current monkeypox outbreak are described. Of note is the absence of reported fever in 10, and the frequent presence of lymphadenopathy, as well as of genital and perianal lesions.

Monkeypox in Europe and North America: What to Expect, What to Do

Data on outcomes of monkeypox cases managed in Europe and North America are limited but provide some clues on epidemiology, clinical manifestations, treatment, and outcome.

Need a Pig Heart? Beware Porcine Cytomegalovirus

The first recipient of a transplanted pig heart died with evidence of infection with a porcine cytomegalovirus.

Human Papillomavirus Infections: We Need to Improve Vaccination Rates

The prevalence of human papillomavirus infections and their sequelae remain high, although this is a problem that is preventable with available vaccines.

HPV Vaccination in Adolescence Prevents Cancer More than 10 Years Later

The authors of this long-term follow-up study of three cluster-randomized trials of human papillomavirus (HPV) vaccination evaluated cancer protection over up to 11 years of follow-up. During this time, 17 HPV-positive cancers were identified in the unvaccinated group, and zero were identified in the vaccinated group, indicating 100% vaccine efficacy at preventing HPV-associated cancers.

COVID-19 Pre-Exposure Prophylaxis

The combination of tixagevimab and cilgavimab (Evusheld) was demonstrated to be effective in the prevention of symptomatic COVID-19, but much remains to be learned as SARS-CoV-2 continues to evolve.