Infectious Disease Alert
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Midlines vs. Peripherally Inserted Central Venous Catheters
Midline catheters are, at a minimum, at least as safe or safer than peripherally inserted central catheters for durations of at least 14 days, thus offering an effective alternative for venous access.
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Infectious Disease Alert Updates
Bloodstream Infections During COVID-19; Ventilator-Associated Pneumonia and Probiotics; Simplified Recommendations for Pneumococcal Vaccination
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Rats in Washington, DC? The Seoul of the Issue
The Centers for Disease Control and Prevention has reported cases of the Seoul hantavirus in Washington, DC.
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Rifampin and Prosthetic Joint Infections
In patients with prosthetic joint infection, no modifiable surgical or antibiotic factors were independently associated with success or failure. Factors not associated with outcomes include the extent of debridement, exchange of mobile parts, use of rifampin or of ciprofloxacin, and duration of intravenous or oral antibiotic administration.
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Delaying Antibiotics in Patients with Suspected Infection Increases Risk of Septic Shock
A retrospective cohort study found that delaying the first dose of antibiotics in patients suspected of having an infection in the emergency department led to a higher risk of progressing to septic shock and in-hospital mortality. Every hour antibiotics were delayed increased the risk of septic shock by 4%.
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Pregnant, Influenza-Infected, and Hospitalized
Almost one-third of women ages 15-44 years hospitalized with influenza were pregnant and almost 5% required intensive care.
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Modernizing Care of Children with Otitis Media
Otitis media usually resolves spontaneously. Antibiotics should not routinely be administered to children with acute uncomplicated otitis media.
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Infectious Disease Alert Updates
Delayed HIV Diagnosis with Injectable PrEP; Fatal Wave of COVID-Associated Mucormycosis
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How Certain Is a Negative Echocardiogram for Excluding Infective Endocarditis?
Applying the proposed strict negative criteria for infective endocarditis (IE) on the first echocardiogram indicated this approach largely prevented unnecessary repeat tests unless clinically indicated for continued suspicion of IE.
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Menstrual Toxic Shock Syndrome
The authors reviewed 102 patients with menstrual toxic shock syndrome requiring intensive care over 16 years in France. Despite the severity of illness, there were no deaths.