Infectious Disease Alert
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Fever of Unknown Origin Due to Cat Scratch Disease
Disseminated cat scratch disease may present as a fever of unknown origin.
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Pneumonia Outbreak in China
A cluster of cases of pneumonia apparently caused by a novel coronavirus has emerged in China.
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Tafenoquine for Malaria Prevention and Relapse Treatment
Tafenoquine is effective for the prevention of all species of malaria and can be used to prevent relapse of Plasmodium vivax and Plasmodium ovale. G6PD status should be evaluated prior to use.
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Impact of Infectious Disease Consultation for Candidemia
A retrospective cohort study found that infectious disease consultation for patients with candidemia resulted in lower 90-day mortality. This was likely a result of strong adherence to guideline- and evidence-based management and the low number of patients who were not treated.
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Treating Ebola Virus Infection
Two monoclonal antibody preparations have been demonstrated to significantly reduce mortality in patients with Ebola virus infection.
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Preventing Ebola Virus Infection
In a scientific/public health triumph, the first vaccine for the prevention of Ebola virus infection has been approved. If administered prior to 10 days after exposure, its protective efficacy is 100%.
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Ebola in Democratic Republic of the Congo: Confronting Potential Disaster
The second largest outbreak of Ebola virus infection has come under control.
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Infectious Disease Alert Updates
Objects of Delusional Infestation; Urine Eosinophils Unreliable; Tecovirimat for Laboratory-Acquired Vaccinia
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Omeprazole Magnesium, Amoxicillin, and Rifabutin Delayed-Release Capsules (Talicia)
The FDA has approved a fixed-dose combination, rifabutin-based (RFB) regimen to treat Helicobacter pylori infection.
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Markers and Mechanisms of Chronic Fatigue Following Mononucleosis
Chronic disabling fatigue affects up to 2% of adolescents and often follows Epstein-Barr virus-related mononucleosis. No clinically significant infectious, immune, neuroendocrine, or autonomic biomarker or pathophysiologic mechanism has been identified to differentiate those with mononucleosis who go on to develop chronic fatigue from those who recover.