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A 61-year-old small business owner was seen in consultation for advice regarding management of a newly discovered pulmonary mass. Seven years previously, he had a 3.5 cm moderately differentiated adenocarcinoma of the sigmoid colon resected along with four regional nodes, all of which were negative for metastatic involvement.
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Aspirin and cancer prevention; rivaroxaban for pulmonary embolism; new rhinosinusitis practice guidelines; and FDA actions.
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In a small, single-institutional, prospective, randomized, placebo-controlled trial, 14 eligible patients (median age 47 years) with clinical and radiographic evidence of radiation necrosis secondary to prior head-and-neck or CNS irradiation were randomized to receive intravenous saline of bevacizumab at 3-week intervals. Patients were followed with serial MRI scans, neurologic examinations, and formal neuropsychological examinations.
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In a retrospective review of 267 patients evaluated at M.D. Anderson Cancer Center with apparent early-stage, node-negative breast cancer, 15% were found to harbor "occult" metastases upon more intensive scrutiny of the axillary node specimens. In this series, long-term follow-up indicates that such discovery was not associated with a greater frequency of recurrence or poorer survival.
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This systematic review and meta-analysis reviewed studies evaluating the implementation of multidisciplinary tracheostomy teams in acute care hospitals.
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The purpose of this study conducted in the intensive care department of the Antwerp University Hospital in Antwerp, Belgium, was to determine if the application of earplugs to reduce sound (noise) in the ICU during the night could be beneficial in the prevention of delirium.
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Although lung-protective ventilation (LPV) is widely acknowledged as one of the few interventions currently available that improves survival in patients with acute lung injury (ALI), it is poorly adopted in practice.