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LRRK2 may be central to the pathogenesis of several major neurodegenerative disorders associated with Parkinsonism.
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This strategy yields potent inhibitors of A-beta aggregation and could lead to therapeutics for Alzheimers disease and other forms of neurodegeneration.
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Further research will be required to understand the pathogenesis of these disorders.
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This condition preferentially affects large myelinated fibers of the posterior roots, may respond favorably to treatment, and may be a restricted form of chronic inflammatory demyelinating polyradiculoneuropathy.
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There is an increase in mortality with methylprednisolone in the 2 weeks after head injury. The cause of the rise in risk of death within 2 weeks is unclear.
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The present findings raise the possibility that new effective therapies may be developed for CMT2A, which target the underlying pathophysiology.
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Researchers from Sweden performed a meta-analysis of 9 randomized, controlled trials that looked at the effectiveness of atenolol on cardiovascular morbidity and mortality in patients with hypertension.
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Clinical trials for a male contraceptive that is a combination of progesterone and testosterone are expected to begin this year.
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I have been a subscriber to Contraceptive Technology Update for many years and rarely take issue with the content. I must, however, register my total surprise and dismay at your 25 Events to Know in Reproductive Health that appeared in the January 2005 issue.
