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Palifermin, a recombinant form of human keratinocyte growth factor, reduced the duration and severity of oral mucositis and the incidence of febrile neutropenia and bacteremia among patients given intensive chemotherapy and radiotherapy for hematologic cancers.
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Amoxicillin-Clavulanate vs Ciprofloxacin; AD Therapy and Cognitive Function; LDL Lowering in CHD Patients; FDA Actions
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Although streptokinase is widely used in the management of pleural infection, a large, randomized, controlled trial showed no benefit in terms of mortality, need for surgery, or hospital stay.
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Is your state next? Laws requiring disclosure of individual hospital infection rates are sweeping the nation. Four statesPennsylvania, Illinois, Florida, and Missourihave passed infection rate disclosure laws, and 20 others have introduced bills.
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A major focus of the recent Conference Retrovirus and Opportunistic Infections (CROI) in Boston in February 2005, was the issue of cardiovascular disease and risk factors in patients with HIV infection.
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Choudhry and colleagues sought to establish the relationship between quality of care with clinical experience by reviewing 62 articles that measured physician knowledge or quality of care as well as time since medical school graduation or age.
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A rigorous operative and pathologic protocol for RRSO increases the detection rate of occult ovarian malignancy in BRCA mutation carriers nearly seven-fold. If confirmed, this finding will alter postoperative management because additional staging, chemotherapy, and follow-up may be necessary in affected women.
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Conjugated equine estrogen alone and CEE + MPA increased the risk of urinary incontinence among continent women and worsened the characteristics of urinary incontinence among symptomatic women after 1 year.
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The accuracy of frozen section diagnosis for the assessment of the ovarian mass is good, with acceptable sensitivities for almost perfect specificities. Future studies on patient preferences for the different outcomes, as well as economic analysis, are needed for definite position of this diagnostic technique.
