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Patients with peripheral artery disease are at high risk for cardiovascular complications. Antiplatelet drugs are routinely prescribed for these patients, but is adding an oral anticoagulant of value?
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Asymptomatic individuals with systolic left ventricular (LV) dysfunction have an increased mortality. Angiotensin converting enzymes inhibitors (ACEI) and angiotensin receptor blockers (ARB) favorably affect such patients, but little is known abut the effect of beta-blockers in this group.
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Biomarkers such as brain natriuretic peptides (BNP) and troponin have been shown to be of diagnostic and prognostic value in patients with heart failure, but little is known abut the value of serial outpatient measurements.
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In the latest issue of Obstetrics and Gynecology there were 3 papers, loosely tied together, that should provide important guidance to clinicians dealing with preterm labor (PTL). One article will be the source for the primary review, but the others will be folded into the comments sections.
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Glass and colleagues from the Kaiser Permanente Northwest Center for Health Research compared breast cancer incidence rates with use of screening mammography and postmenopausal hormone therapy prescriptions between 1980 and 2006.
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High-Dose Statin Therapy, Value for Older Adults; Simvastatin, Best for Parkinson's Disease; Polyethylene Glycol for Chronic Constipation; FDA Actions
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Richards and colleagues representing the Canadian Multicentre Osteoporosis Study Research Group reported the effect of daily selective serotonin reuptake inhibitors (SSRIs) use in a prospective cohort study in 7 regional centers of 5008 adults over the age of 50.
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Ovarian cancer patients relapsing within 6 months of their primary therapy represent among the most challenging patients to treat. Generally, in this setting, most patients have only been exposed to one or two agents, yet they are phenotypically resistant to most chemotherapeutics, making drug discovery of paramount importance.
