Clinical
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Pregabalin Improves Outcomes in Chronic Cough
Pregabalin appears to provide meaningful improvement in cough for patients who have been refractory to other standard interventions.
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Patient Health Questionnaire and Suicide Ideation
Clinicians should take positive results on the Patient Health Questionnaire seriously and institute appropriate suicide prevention methods.
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Severe Hypoglycemia: Identifying At-risk Groups
Hypoglycemia is such an important obstacle to optimized goal attainment in diabetes.
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Who’s Right About DPP4 Agents and Heart Failure?
Other DPP4 inhibitors such as sitagliptin or linagliptin should be considered when clinicians wish to use a DPP4 inhibitor in patients with heart failure.
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Home BP Monitoring vs Ambulatory BP Monitoring
Clinicians should routinely use ambulatory blood pressure monitoring or home blood pressure monitoring prior to initiating treatment for hypertension.
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FDA Actions
In this section: boxed warning to all immediate-release opioids; eased restrictions on mifepristone used with misoprostol used for medical abortions; reslizumab for the maintenance treatment of severe asthma; and ixekizumab for the treatment of adults with moderate-to-severe plaque psoriasis.
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New Guidelines for Dual Antiplatelet Therapy
The guideline recommends a minimal therapy duration of 6-12 months, while therapy beyond 12 months should be reserved for patients at the highest risk of a vascular event.
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More Evidence Supports Timing Hypothesis for Hormone Therapy
More evidence that supports the timing hypothesis (or the critical window-of-opportunity hypothesis) for hormone therapy to slow atherosclerosis progression.
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Federal Agencies, States Move Swiftly to Combat Opioid Overdose Epidemic
CDC issues new pain management guidelines; White House, states bring own ideas to the table.
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Chest Pain and Giant T Wave Inversion
Chest pain (rather than shortness of breath) and ST elevation (rather than T wave inversion) in leads V1 and V2 make massive pulmonary embolism unlikely.