Clinical
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Is an Even Safer Combined Oral Contraceptive Pill Available?
ABSTRACT & COMMENTARY: New study has many advantages, including ascertainment of important confounding variables.
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Clinical Briefs
In this section: debunking an asthma treatment; more questions than answers with perioperative statin treatment; and another reason to stay away from cocaine.
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Lixisenatide Injection (Adlyxin)
Lixisenatide is indicated as an adjunct to diet and exercise to improve glycemic control in adults suffering from type 2 diabetes mellitus.
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Dual Antiplatelet Therapy Appears More Effective Than Single Therapy
It appears short-term dual antiplatelet therapy is superior to prolonged treatment, but a difference in outcome must be confirmed by further well-designed randomized, clinical trials.
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Greater Weight Loss Later in Life Associated with Increased Risk of Mild Cognitive Impairment
In a population-based, prospective study of subjects ≥ 70 years of age, increasing weight loss per decade from midlife to late-life was associated with an increased risk of incident mild cognitive impairment.
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Wheat Causes Intestinal Immune Activation in Some Patients Without Celiac Disease
Some patients without celiac disease may exhibit wheat sensitivity with demonstrated intestinal epithelial cell damage.
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Too Little of a Good Thing Can Be a Bad Thing
A healthy lifestyle may substantially reduce the burden of cancer.
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FDA Actions
In this section: FDA approves generic influenza treatment; major pharma loses statin battle; FDA gives thumbs up to agonist to treat type 2 diabetes; agency green lights dry eye disease solution; and approves over-the-counter acne treatment.
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Study: Knee Replacement Can Lead to Chronic Opioid Use
Total knee replacement is the surgical procedure most commonly associated with chronic opioid use in opioid-naïve patients.
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Report: Certain Drugs Cause, Exacerbate Heart Failure
New recommendations for clinicians treating heart failure patients include comprehensive medication reconciliation, evaluating risks and benefits of every medication, and discontinuing medications when possible.