Browse Clinical Articles by Topic

Genital HPV in Men: How Common Is It?

In this U.S. cross-sectional survey, the prevalence of genital human papillomavirus (HPV) infection in adult men was 45%, of which 25% were high-risk subtypes. The overall rate of HPV vaccination among those who were eligible was 11%.

Dual Antibiotic Therapy Is Not Routinely Necessary for Uncomplicated Cellulitis

A randomized, multicenter, placebo-controlled clinical trial that enrolled patients presenting to emergency departments with uncomplicated cellulitis found the addition of trimethoprim-sulfamethoxazole to cephalexin did not lead to better outcomes.

Separating Celiac Disease From Non-celiac Gluten Sensitivity

As there is no diagnostic test to confirm any patient’s 'non-gluten celiac sensitivity,' debate on the issue continues.

Azithromycin Reduces Asthma Exacerbations

Asthma exacerbations essentially are induced exclusively by viral infections (as well as thermal and atopic stimuli). Is it time to reconsider that posture?

BCG Vaccinations and the False-positive Effect

Clinicians should consider that the bacille Calmette-Guerin vaccination effect could influence tuberculin testing responsivity for an essentially indefinite period.

Measuring Urine Calcium in Nephrolithiasis Patients

High sodium content in the diet increases calcium excretion in the urine, so sodium restriction may be beneficial. Thiazide diuretics reduce urinary calcium excretion and are useful when dietary and hydration steps are insufficient.

Managing Diabetes: First Things First, or Vice Versa

Certain attributes suggest glucagon-like peptide-1 receptor agonists might be an appropriate initial treatment for type 2 diabetes mellitus, supplanting metformin.

Routine Preoperative Lab Tests for Elective Surgery

Historically, there have been an excessive number of pre-op tests performed that not only provide no benefit for patient outcomes, but actually may cause harm because of unnecessary expense as well as need for follow-up of incidental (usually irrelevant) abnormal findings.

FDA Actions

In this section: The agency approves fixed-dose combination hepatitis C treatment, greenlights first U.S. gene therapy, and approves new urinary tract infection drug.

Treating Pain and PTSD with Cannabis

There is insufficient evidence today to draw conclusions about the benefits and harms of plant-based cannabis preparations in patients with PTSD.