Clinical
RSSArticles
-
Rheumatic Heart Disease — The Global Situation
With advances in access to good medical care, the global burden of rheumatic heart disease is declining. However, there still is significant disease in resource-limited regions of the world.
-
Chagas Seroprevalence in Military Personnel in Texas
A cross-sectional study of military trainees and instructors who spend significant time in field conditions was performed at Joint Base San Antonio to determine the prevalence of Trypanosoma cruzi infection. None tested positive by polymerase chain reaction nor by enzyme-linked immunosorbent assay or indirect immunofluorescent antibody.
-
Extreme Weather and Infectious Diseases: What Will Follow Hurricanes Harvey and Irma?
Among the dangers faced after a severe weather event is an increased risk of various infections.
-
Zika Virus Disease: A Primer for the Primary Care Physician
Zika virus disease is a global issue, but with the recent hurricanes and flooding in Texas and Florida, mosquito-borne illnesses may become more prevalent. This article discusses the latest recommendations for the prevention of Zika viral disease, the populations and regions still at increased risk, and the latest and most promising research being conducted to develop a Zika virus vaccine and treatment.
-
Anomalous Coronary Arteries Discovered in Middle-aged Individuals
Anomalous origin of coronary arteries from the opposite sinus are encountered more frequently in middle-aged subjects evaluated for coronary artery disease using CT angiography.
-
Natriuretic Peptide-guided Therapy Does Not Improve Systolic Heart Failure Outcomes
Among high-risk patients with heart failure and reduced ejection fraction, a strategy of titrating medical therapy to a target natriuretic peptide level was not associated with improvements in hospitalization or survival.
-
Rate-controlled Atrial Fibrillation as a Reversible Cause of Cardiomyopathy
In patients with persistent but rate-controlled atrial fibrillation and left ventricular systolic dysfunction of otherwise uncertain etiology, catheter ablation to restore sinus rhythm can result in significant improvement or normalization of ejection fraction.
-
Is a Dabigatran Reversal Agent Effective?
A pragmatic clinical study of idarucizumab for counteracting the effects of the oral anticoagulant dabigatran showed rapid and complete reversal of its effects in patients with major bleeding or urgent surgery, without any adverse safety concerns.
-
RE-DUAL Deals Another Blow to Triple Therapy
In this trial of post-percutaneous coronary intervention patients with atrial fibrillation, dual antithrombotic therapy with dabigatran and a P2Y12 inhibitor showed lower rates of bleeding but similar ischemic and thrombotic outcomes compared to a triple therapy regimen with warfarin.
-
Subclinical Hypothyroidism: What Is It and When Should We Treat It?
The current diagnosis and treatment of subclinical hypothyroidism in women of reproductive age is controversial and may well change as new studies become available.