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Ivermectin is a well-known anti-parasitic medication that has been used for years, with little toxicity to humans.
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Cryptococcal infection has taken another new twist. For years before the HIV epidemic, infection with C. neoformans mostly occurred in immunosuppressed individuals who also had some defined zoonotic exposure, often to birds or pigeons.
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A physician in new York notified relevant county and state public health authorities in August 2009, of a patient from Rochester with suspected dengue, subsequently confirmed by CDC, whose only travel had been to Key West, FL. Confirmation at the CDC included both serum antibody testing and detection of dengue virus serotype 1 in cerebrospinal fluid.
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In a prospective study of the actual oral nutritional intake of patients with respiratory failure in the first week following extubation, average intake failed to exceed 50% of daily requirements on all seven days.
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In this retrospective study of patients hospitalized because of severe chronic liver disease, venous thromboembolism was relatively common and "auto-anticoagulation" in the form of an elevated INR had no apparent protective effect.
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The use of angiotensin converting enzyme (ACE) inhibitors in all acute myocardial infarction (MI) patients is controversial. Thus, these investigators from the Register of Information and Knowledge about Swedish Heart Intensive Care Admissions (RIKS-HIA) examined the association between ACE inhibitor therapy and mortality in unselected patients with acute MI.
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Serious infections caused by Acinetobacter baumannii are appearing in the community, spread by patients who acquired the organism in the hospital setting, and conversely, the organism is being introduced into the hospital from long-term nursing care patient settings. Resistance to antimicrobial agents has increased over the six-year study period, along with the severity of disease.
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Early antibiotic administration was associated with reduced likelihood of death, mechanical ventilation, and readmission (but increased risk of Clostridium difficile infection) among patients hospitalized for acute exacerbations of COPD.
