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Everolimus, a derivative of sirolimus, is a mammalian target of rapamycin (mTOR) inhibitor.
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Testing patients with abdominal symptoms for celiac disease in primary care settings using IgA tissue transglutaminase antibodies and IgA endomysial antibodies yielded high sensitivity and specificity, justifying their use widely for diagnosis.
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Ketorolac nasal spray is indicated for the management of moderate to moderately severe pain that requires analgesia at the opioid level.1 It is indicated for short-term use only (up to 5 days).
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Vitamin B12 levels fall, and continue to fall, with continued metformin use in patients already receiving insulin.
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In community-dwelling women age 70 years and older, annual oral administration of high-dose vitamin D for 3-5 years resulted in a higher, not lower, incidence of falls and fractures.
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Because it is recognized that type 2 diabetics (DM2) incur greater risk of CV outcomes than the general population, consensus groups have advocated BP < 130/80 mmHg as a preferred goal, in contrast to 140/90 mmHg for the general hypertensive population.
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The ECG shown above was obtained from an 88-year-old woman who refused treatment. What is the rhythm? Is there a grouping? Is anything else going on?
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New reports about proton pump inhibitors and the effects of gastric suppression, pioglitazone vs vitamin E for non-alcoholic steatohepatitis, metformin and vitamin B12 deficiency, and FDA Actions.
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Although some aspects of vaginal birth after cesarean delivery (VBAC) have been covered in previous OB/GYN Clinical Alert issues, I cannot pass up an opportunity to comment on two papers appearing in the June issue of Obstetrics & Gynecology.
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Carcinosarcoma of the uterus is a rare condition accounting for less that 4% of all uterine neoplasms. Previous work has identified that the most active single agents are platinum, ifosfamide, paclitaxel, and doxorubicin.
